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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TOP3B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8940 Official gene symbol TOP3B Full name topoisomerase (DNA) III beta Aliases ,FLJ39376, Gene summary This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq] Location Chromosome: 22   Locus: 22q11.22 Gene position 22337147 - 22311403  Map Viewer Gene orientation minus Gene size 25745 bp Gene sequence >TOP3B:complement(1701972..1727716):Length=25745 GGATCCGCGGTGCGGCTGTGGGTGAGCGGCGGGCTGCGGGACCCTCGCCCGGCGGCTCAG AAAGGCGGGAAGCGCACGCATTTTTCTGGCTTGTTTCCTGAACGTTGGCCGGCGGAGGAC CCGCGAGCTCGGGAGAGCGCCCGGGCCGGGCTCTGCATTCTTGTTGCCTCTTCCCTGGCG GGGGTGATACTCTCCCGCGGGGCTTGCTGTGGGGGTTCAGGGAGGTGGAGATGGGCCCGC CATGTGCCTGCAGGGAGCAGGCGCTGTGGTTAATACTTTTCTTCTTCGAACCCTCCCACA GCTCTTTAGGGTGAGATCTGCTGTACCAGTCTCACAGGTAGGGAAACTGAGGCTCAGGGA AGCTGTGCAGCCACCGGGGCCCAGATCGGTGCGGTACACACCCAGGCAGCTTCCACTCGC CGCCCCCTAGGCCCTGGCTGGGTTTTGAGGGCACCCAGGTTCTCTGACCTGTTATCTGTA AATGAAGTAGGGTACTTTTGTGAACAAATTAGCTGGAATCCAGGGGCAATAATTTCTCGC AGAAGTGAAAGGTAAGATGTTCCTAGTCTTGCCTTTTTATCTTCTCACCTTTTGAAACAG GACCTGAGAGGCCAGCCTAACTTGGGCTTGATGGCCAGCCAGTCCTGGGATTCTTTTGCC AAGGTCACCTGACACTAGTGTGACTTGTTCTGAACCTCCATTTACTCACAGTTTTAAAAA ATTACAACACCTGCCTTATGGGGTTGCTGGCGAGATTGAATAGTGTTGATAGCTATGGTG TGCCTACTACAAAGGAGGAGCTTAAGAAATGGTTGTTTCCCTCTTTTCCTGATTCTAGAA GCATTTGGTAAAGTTACTGAGGTGGTAAATCCTAGGAATTTTAATGCTATTCAGACCACT GCTAGGCCTACTCCCAGGCCACATCTGCTTGTTTCTTTTTTTGTTTGTTTTGTTGCAGGC AGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACC TCCGCCCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGG CATGCGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACCAGGCTTCACCATGT TGGCCAGGCTGGTCTTGAACTGCTGACCTCGGGTGATCCACCTGCCTCAGCCTCGCAAAG TATTTGCTCACTGTCTATTTACCGTGAGAATGCACAAAGCAAAACCCGTGTTCTCCTGCT GCTTACTTACTTTCTAGGAGCTGTAAGACAAGAGCTGAATAAGTAGATGGAAGCTGTACC AAGTGTAGTGATGAGTGCTACAAGGAAGCAAAGCTGGGCTGCTGTTCCATCAGAGTGCTC ACAGAGGCAGGACAGGATCAGGCTTGGGGCACGGGTTCTAGAACAACCAAGTCCAGCCAC TGGAGCTCTGGTCTCTCTGACCCCACAGTCCCAGTCTAGGCCAATAAAATGGCAGCACCT ATTAGCATCCCTGCCTAGGATGCTGGCAGGACTGCCTGGTCCCTGGTGTGTCCTCATTAT GTCATACATAATTGCTGACTACTCTGTGGCATAGACATGAGAAAATCTGAGGAAACATTT TAGGACAAAATTTCCTACTTTGGAAGAGATGGGAAACTCAGACCCTCACAGAACAATGCC CCTCTGCTGCGAGTTTTCCCTTTTGGCCTCTGGCTTCCCAGGGTGAGAGAAGGGGAGTCC CTAAATCTCTTTTAAACCTCACTTCTGGGCCTCTGATTTTGGTAGAATCAAAACTTCCCC AGAACGGAGAGCAGAGGCCAGTCATAATCACCTTGGTTGTTCATTCATTCCCTCAGCAGG CATTTAGTGCATGCTGGGTGCCAGAAATATGGCAATGAACCTGACAATTGTGGGAGAGAC AGACTGCTGACGCCAGATGCAGTCTTCAGGAGGGGAGGGGCAGGGGTCAGAGCAAGTAGA CTAAGGGGGAAAAGTGGCCTAGGCCGAAGCCTGCTGGCGCACAGGGAGGAAAGGTGGGTG CGCAGCAGAGCCTTGGGAGATGCAGCTGGAGCTGTCATGGGCCAGAGAGCTCATCTGCAG ACAGTGTCGTCATTCCACAAGGCCTCGGCTCTTTCACTGTGGGATGGTTGTACATTTAAG GGGAACATCCACTTACTTATTTTGAGGAAAAAAGCAAATTGTCATTTTATTTGGGACAGC TTTCTGGTCAAGATTACTGATTTCACTGTAGTCCTGTGATCTCTTAAGTGGGGAACAAGG TTGACAGCCCAAGGCCGACCTTGGACCTCTTCCCCTGCACAGCATGATGAGCAGCAGAAG CCCCTTTAGTGAGGGAGTTCCTTTGGCATCCTTTCTGAACAATGCCCTTTACAACCCTCC TTTATTTTTCTGGTTTTATTGTAAAGTCCCTTGTCTTAGTTCTTGTCCCTCAGTCACCTG TGTCCAGGCGCTAAATGTAAAAGGTGCAAAAGGGAATGTGGTGAGGAGGCACCCCCAGCC CTGACCTCCAGGCCCTAACACCCACTCCAGGTGATTGCTTGGACTGTTTGTTTTGCGTTC CATCCAGACATATCGCCTCTTCATAATCAAGTGCACACGTGTGCACACATATGTGTGATC ACAGATGGCAGTGCTCTCTACACACCGTTACATGCCCAGCTTTCTTAGCATGATTTATTT CAGTGATCTGATCCACGTTAGTATGTACCAAGCAGATGCTTTCCTTTGTAATGCTGCCAG GTGCTCTACTGTAGAGAATGCCATGCTTTTTTTTTTTTTTTTTTTTTTTGGAGATGGAGT CTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGC TTCCCGGGTTCACACCATTCTCCGCTTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTC CCGAGTAGCTGGGACTACAGGCGCCTGCCACCATGCCCAGCTAATTTTTAGTATTTTTAG TAGAGACGGGGTTTCACCACGTTAGTCAGGATGGTCTTGATCTCCTGACCTCGTGATCTG CCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAGAG AATGCCATGCTTTTATTTAACCACCTCCCTGTTGACAGACACCAGCTTGTTTCTAACCTT TTATCATGATTGATAATGCTGCAGAGAACTCCCCAGTGATGTGGTTCATCACAGGCACCA CCGTGCCCAGCCTGAGGCCACTCCAGCGCTGCCCTGTCCTACCTCCTGGGGACTCAGAGT CCACATGGACAGTCTTGTCAGGGCCCACCACTGACTCCTGTGAGTCTCCCCAGGTGACTT CACTCTCTACCTGTCTCACAGCCCTTGCCCTCCCTGGGTCAGCATGCCACCACCCAGGCC CCTCTGTAATTCCTGTTTGAGCCTCCCACCCTCTGGGAGTTGCTTCTTTGACTCCCACTT CCTGCTCTTGTGCCTCACTTCCTGGACCCCACAGAGCACACCCTCTGTGGACCCTCCCCA ACCCTCACCTCCCTCTTCACCCAACTCAGAGTCAGGTTCTGTCCTTGTAATCTCTCCCCT CGAACCCTGACCCACTCCCTCTCCCTCCTACTCACCTGGACTCTCCCATCTAACTAAATC CAGTGCTTCCTCTGCTGTGGGCCTGCCCGCAGCATCACCACCTGTCCTCCCTCAGTGGAC AGCCGTACCATGCCTCCTCCTCCACCAAGAGAAGTGCAGCCTTGTGGCAGCTCTGCATCG CCTGGATGCTGACCGGCTGCCTCTCTTGCCCCTCACCCTCCCAAGGCCATCACTGCAGCA GTTCCTTCCCCTCCGGCACGCAGCTTCTCTTTTCCTTCTCGCCAGAGCAGTCCCATCAGC GGAGAACATGCTGGCACAGCCACCATCCTGAAACAAGAGGGGACAGTGCACCAGCCTTCT CCCATCTCCCAGGTTTTGTTGAGCTCACCCCATGCAGCTTTCATCTGTCACTCACCACAT GGCCCCATCAGGATTACCCAGGGCTCTGTTTGCCAGACCCTACAGTCAGGTCTCAGCTGC CATCTCGCCTGGCCTGTCAGTGTCCCCCACATGGTGATAACTGCCCTGAAGTGCTCTTTC CTGTGGCTTTCAGGACCTTACCCCTCCTGACTCACCCTGCTAGCTCCTCATCTCCCGACC CCCAGCCTGGGCTCCTTCCACATTGCTGCCACCTCCTCCAGGCCACCCAGGCTGTCCAAT GGGCAGGTCCCGTTTAACACACCTGAAGTCCCACATCAGACTGCCAGTCCCTTCCTGTCA TGCCTAAGCCAAAGCCATGGGTTGTTCCTTTTGCTTTTTTGTAAAGATGAGGTCTCATTG TGTTAATCAGGCTCTTCTCAAACTCCTGGCCTCAAGTGGTCCTCTTGCCTTCGCCTCCCA AAGCACTAGGATTATAGGTGTGAGCCCATGGCAGGTGTGAGCCCATGCCCAGCTCTGCCT CAGGTCATTCTTGACTCACCTTCCCCTCCCCCTCCCATGTCCCGCCATCCCAGGTCTGCC TGGATTCTGACTTCCCTCGCATCCTCCACCACTGCTACCCAGGGCCCATTCATCCTCTTC TATGTGGCAGCCAGAGAGGTCCCTTTAACACTTGAAGTCAGATTATCCCACACCTATGCA AACCCTCTGCTGCCTCCCAGCACCCCTAGAGCAGACCCACATTCTACACCCCTGCTCCCT CCCTCAGCCCCATGAGCCCCCCTGCCCAGCCATATCCTCCCCAAGGACCTCACCTTCCCT GCTCCTTCTGCCTGGACTCTTCTCCCAGGTGTCACCCAGCCCTGCCCTGTCCCTCCCCTG CTCCCATACTACAGCATGAGTTCTGGGAGGGCAGGACCTGGTGTTGCTTTGTGCTGTATT CCCTGCATCCTGGACTAGGCCAAGCATGCAGTAGGTACTCAATAAATAACTGGACTATTA AGTTCATTCCAAGGAGTGGAATTGCTGGGATGTGCACTCGGACTTTGAGAGGGATCCCTG AATTGCTGCACATAGAGGTTGTTCCCATTTAACTTCCCCATGCCCTCATCTGCTGTGTGT GCAACGACTTTGAGTCTCTCCCTATGTGATAAGCACAAGCTCATTGTAGTTCTGAGTTTC TTCTGCGAGTGTTGTTGGACATGATGTGATACCACAAAGGTACTTACGTGGTGGTTTTCC CTTTTTTTTTTTTTTTTTTTTTTGTTTGAGATGGAGTCTCGCTCTGTTGTACAAGCTGGA GTGCAATAGCATGATCTCGGCTCACTGCAACCTCCACTTCCTGAGTTCGAGCGATTCTCA TGCCTCAGCCTCCCAAGCAGCTGGGATTATAGGCACCCACCACCACACCCAGCTAATTTT TGTATTTTTATTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGAC CTCAAGTGGTCCACCCACCTCAGCCTCCCAAAGTGCTGGGATACAGGCGTGAGCCACTGT GCCCATCTAGGTGGTAGTTTTTCTTTATGCTGAGATTATTTTATTTTGCTTTTACTTTTT TTGAGACAGGGTCTTGCTGTCACCTAGGCTGGAGTGAAGTGGCTGTTCTATCCACAGGTG CAGTCATGGCACACAACAGCCTTGAATTCCTGGCCTCAAGCAAGCGATCCTCTTGCCTCA GCCTCCTGAGTGGCTGACACTATAGGCATGTGCTACCACACCTGGCTTGTGAGATTTATT TTAAAAGCACATGTTTTTCCTAATATTTTCTGGTTTCATTGTTTCTACTCAAACCTTTGC TAGATCTGGAATCGGTTTTAGTGGGATTTAGGAAGCAGGAGTCTAACTTTATTTTTTTTC ACAGCAGATTTCCCAGTTGTCTCAATACGAGTCTTTTTTTTCTTTTTTAATACGGTGCTA TGTTTATAAACATCAGTGCTACATTTATAATGACTGAAAAAACAAAAAGGGTTCATGTGG TTTTCTTTTACTTGGCTAGCAGGTATTGAATGTCATGTGTCAGGCACAGAAAGCTGTTGC AAAGACCAACAGTGATTCAGACACAAAGCCCATCGTGTCCTATTTTGGGGGTGAAGTAGT CGCTGATGATGGCATGATGTGAGTGGGTTGGAATGGAGACCTAGCCCAAGAGCTGTGGGC ACAGGAGGGCTGACTTACCCTGCCAGTGGTGTTGGGAGACTTGAGCTGGGCCTGTGGGCC ATCCAGCTGCATCCTCCAGGCCTGGCGGAGCTTTCTCTCAGGCAGGGAAGCGCAGGCACA GAGGCTTCAAGTGCGTGTTTGCTTCGATGATGATATTTGATTTAATTTGGCCAGAGCATG ACCTGCAAAGCAAAAGGTGGAGTGGAATAGGTGGGAGATAGATGTGACAGAGTCCTGATG TCTGCTTGGGGCTGGACCGACTAGCCAGAGGGTCTCAGGCCCATCATGGATCAGAAGGAC CTGGGGGGCCCAGCCTGGGCATCTGCATTTTGTAAAGTGTCCTGGGGCGTCCAAGTGCTT TGCTGAGCGGGAGGTGCTGCTCTCGGCCACGATAGTTCCTCTTTCCAGGTGAGTCCACCT GTAGGTGGAAGAGCCAGTCCAGAGAGGAGGGCCAGGCATCCACCTGGCCTGACCCATCAC TCCAGATCCCCAGGCCCCAGCATCTTCCTAGCATGGATTTAGGAATAAAATTGACCTGAG ATCACTGGGGCCACTTCACCTTCCCCCAAATGGAGCCACATTCCCAGGATCATCTCAGCC ACTTCAGCTGACCTGGTAGTTTTTTCTTGTTTTTAATCTCAGATGTCTTCAAGTTTCCCT AATTCCCTAATTTTTCTTCTTCTTGCCTCAGGTTGGTCTTGTTTTTTCTTTGTTAAAGTG ATTTTCCTTGTAGTGGTGTAGGTTCTATTGACAGCATTGCTATCCTGAGTGTCTTTTCTT CTCTTTAGGAGTCAGCATTGGTAATAGTGCTGTGCTGCGGAAGAGTGGAGTCTAAACTTT TTCATTGCCAGTGCCCCGAAACTGGAGTGTGAAGGACCGAGACAAAATGAAGACTGTGCT CATGGTTGCTGAAAAGCCGTCCTTGGCACAGTCAATTGCCAAAATCCTCTCTAGAGGTAG GAGAGACCAGCCCTGCTTTGGTCTGTAAGCACGGTCGTTTATGTGTTACAGGACATTTTT TCCTAATGTGATTCCACCCTGGCTGGGGTAGATTTGGTTCGGGTCGGCAGGTGGTAATGA AGCATCTCAGTATGTCACAGTGGGGTGCATTTGCTTCCACTCCTGGCAATGTGCCAAAGC TGGGGTTCCCATAAGGCACAAGGCACAATTTACAATGAAATTGAAGGACAGTCATTATCC ATATGCTGGGCCTGGTGGGGCTATTAGGTACAGGTAGTAGAAACCAGCCCTGGAAGGAAG GAGACGCAGCCAGGACTACACCCCAGTCAAGGTCTGATGAGGCTATGCCCCAGGCATTGT CACCCCTGGATACTCCCACTGTCCTGTGGACCTCACGTCACTCCAGAGTAGCCAATGGAC TGAGCTATGGCCACAGGCACTACTGAGACACCAGGGAGCTCGAGAGGGAATGTCTGCCAC TCACCCCCAACTCTGGCCACTGGGGTGGTTGGTAGGGTGCTGTTTCCCCCTATCTTTGAA TTCCCTCCAAATAGGAAGAGTTTTAGATGCTGGGTACCCAGAAATGACAGGCACCTACCT GGCCTCCCCTTGGTCCAGCAGTTGAGAGGGGAAGAGACCCTCGTTCAGCTGAGAAGGCAT GGTCCGCAGGGGACGGTGCCCCAAAAGTGGTGCCCGGTGCCCAGAAGCTGAGAAAGTACA GCTGAGTATGGTCAGTGGAGAGGGTGAGAATTCGATAATTAGAAGGTCCCTGGTAACCGA GAGTAGATCTGGAGTCTGTTTTAGTAAACGATGAATAACGTTTCAATGAAGTGAGGCAAA AATGGAATTGAAGAGTGAAAACATAAATACAGAGAAAGAGCCCACCCCTGCCTGCTCCTG GCTCCCGGCAGCCTGGGGCTCTGCATCGAGAGTGCTCTGTGCTAGGTTGTTGGCAGATGC TGTTTTCCCTGAGCGCCGTCCCACCTCTCAGTGCCCAACTACCCGCACCAGTCTGCGGAA TGTCGTCACTCACCACTCTGGGGAAGGAGGACTCTGGCCCTCTGGGAGGTGGCATCCGGG CTGGGGTCTCCACAGGGTCTTCAGCTCAGCTGAAGCAGCCAGTCACTTTGTGCTTCCTCA TCCCCAGGGAGCCTGTCCTCACACAAAGGGCTGAACGGGGCCTGCTCAGTCCACGAGTAC ACTGGGACCTTTGCTGGCCAGCCAGTGCGCTTCAAGATGACGTCTGTCTGTGGTCACGTG ATGACCCTGGATTTCCTGGGTAAGCCCCTCTACCCTCCATCCTACTGAAGGGAGTTCTGC ATGGCACTGGCCAGGGTCCAGTTGAAGCCAGGAGATGCCTCTAGGCAGGGAAGTTTGTCC CAACTCCATGAGTCATAAGGCCAGCAGATCATGAAGTAGCAATGAGAGGGTCCCTGGTGC GGTGCCCAGAACCCAGGCTCTGGAACTCAGCCCTGGGTCCCCATCATAGCGGCACCCCTT AGTCGCTGCATTCCCTGTGTGCCTTCCTATGTAGACAAAGTGGCAGCACCTATCTTAGGA AGGGCTTGACCTGTGCAGGCATTTAAGAGAAGGCTGCTGCTGTTGCCAAGTTGACCGTCA TCTGTCGGTCATTTGGTGGCTGTCGTTGTCATTCCTATATTGTTACTGTTATCAATTACC TTGGAAGCGCCAGTATTAGTGACCTGCTGGGTGTAGGTTTGGGGCCATGTGGTTGGCAAG AGTCTGATCCAGGCTTTTCCCCCTGCTCTGCCGGCTCACTGGCTGGGGATGTGGGCAATG ACGGCCTCTGAGTTTACACTTCTCATAGTGAAATGGGTCTCACAGCAATGCCATCTGCTT CCCAAGGCTAAGGATTCAGTGTGACAGTGAGGGCAAAGCACTCAGCACAGGGCCCGACAC ACAGCAAAGCCTCAGCCCTTGTTCTTGCTGCTCATTGATGACAGTGATGACAATGATGGT GACTGAGTTGTGTGGCTGAGCATTTGGACCCCAAGTTTTATCTCCAACTGGCAGGTGGGG AGCCGGGATTTGAATTTGGCTCTGTCTGACCCCATTCTCCCAGGATGCAAGAAATGGGGC CTGGGGAGGATCGCTTGAGCCCAGGAGTTCAAGACTAGTCTGGACAACATAGTGAGACCC CTGTCTCTACAAAAAAAAAAAAAAACAAAATTCTTTTTAAATCAGCTGGCATGGTGGTGC GCACCTGTAGTCTTGGGAGGCTGAGGTGGGAAGATGGACTGAGGCTGGGAGGTCGAGACT GCAGTTAGCCGTGATCGTATCACTGTACTTCATCCTGGGTGATAGAGCGAGACCCCTGTC TCAGAAAAAAAAAGAAATGGGGCCTAAAAGAAAGCCAGACAGCTGAGCATGCAAGAACCG GGTCTCTGTAGATGAGTAGGTGAATGTGCTGGGCATGAGGCTCAAAAAGATGGTCCTTTA ACAGGAACGACTGCACACATGTGTGCCCCCACAGAGTGCTGGGTGGAAGGACAAAGTTCC AGAAACTCAGGTTGGAAGTGTCAATGAAGGCACCATTGTGGGGTCCAGTGCTCAGGCAAA GAGACCCAGCCCAGGAATGGTGCTCCCAGCCACAGGGAAAGTCCCGGAAGTGAGGCCAGA GTGGCAGCCCCCCGAGAGCTTGCTTGGCTCCTGTGGTTGGCCGGGGTGTGGTGGGTCCGC TCAGCAGCCGAGCAGAAAGGAGGCTGGATGGGAGGGGGTTACCAAAGGCCTGAACCCACA TCCTGGCTCTGCCTCTGATCATCAGGATGACCCTGGGCAAATTGTTCTCCAAGCTTTCCC CTCCTCATTTGTGGGATGAGGCCAACATCCTCCTGGGGTTATGATGGTCTCGGAGGCTGA GCTCCTGTGACTCAATGTCACTGTGACTGGTTTGTAGGAAAATACAACAAATGGGACAAA GTGGACCCCGCAGAACTGTTCAGCCAAGCTCCCACGGAGAAGAAAGAAGCTAACCCCAAG CTGAACATGGTGAAGTTCCTGCAGGTGCGTGGGGCTGGCCTGGGCATGAGCACACCGGGG CTCCCCACCCTCCACAGCTGCCATGTCTTTGCCCACCCTTGCTTGAGTCCTAATCCCCCT TGGACAGGGGGGCCTTTGCTAGCTTTTTCTGTGAGTGCCCCCTGCTGGCCCACGAGGCAC CTGCAGGCACCCCCAACACACAAGGCAGTTGCCATTGCCAACCCTCAGTCCTGGAGAGCA GGCCTTCTGCTTTTAAAATAGCTTGTTTGGTCGGGGGGTTTTTCTCCTTAATTTTAAAAC AAATGCATACAGATTATGGAAAATTAGAAAGTGCAGATAAGTAGAAAGACAGAAAAATTA TGCATAATCATATTACCCAAGACGACTGCTGTTATCATTTAGGGTTATTTCATTTTAACC CTTCTTCTGGGCAGTTTTGGGGTATAAGATCATGTTGCATTTATACTTTTTTTTTTGGTC CAAAAAACATCAATTATAAACTCAATTCTTTTCTGTTGGCTGAGCCAGCCTCAACACAGC CAGCTCCTTACCCAGCCCAGGTACCAGTCCTCCTAACTGAGGTTCAGGGCCTGGGACCAA GCCCTGTCCTGGATGGGAGCACTGGGGGCGGGTGGCACAGACCGGGTCTGCAGCAGGTAC GTGTGAACCTGTGCTGTGTGGCAGGTGGAGGGCAGAGGCTGCGACTACATCGTGCTGTGG CTGGACTGCGACAAGGAGGGGGAGAACATCTGCTTTGAGGTGAGTGTGAGGCTCACTTTG TTCCTCACTTTTGGCCTTTCTGACACCAGCCCCAAACTGACACCAGCAGTCAGTCACATC ACTCCTGGGGCCAAAGGAGGGAGTAAACTGTACCGGTTTAAAAACACCTCTCCCCTCCCT TTATTCTGAAACTCCACAGATACTTTTAACTGCATAGGCTCTATTAAAGGTGGTCAGTTG TTCCTCCGCTTGCTGAGGCCTCAACGGTATGAGTGAACATAGGAGGGGCCAAATTGTCTG GGTGGATGCAGGTTTCAGAATGGGATTGTCTTGGGGCAGCTTGGTGTTCAGCATCTTGTG CCCAGCGTGACTTCTCAGGGACCTTGGGTTGATGCTGGTTGATTCCCGACCTCAGCACTG AGCTCCTTTTGCAGGCCTCGCTCTGCTCATCTCCTGCCTCATCCAGGATGCCTCCTGCCT CCAGCCAACCCTGGGAGCCCTGCAGAGAAGCAGGTGGCAGCTGCTCCCTGTGCACACCCC ATGCCCCATGCTTGCCCCGGCCATGGTGCCCTCACAGTGGCCATGACTGCTGGTCTCACT TGGTGCCCTTCAGACTGTTGTTCTATGGGTCGCCCCCGTGCTCCTGTACCCCCAGCTCTC ACCCGTGGCTCAAGAGCTGGTCAGTGAGACAGAGCTGAGGCACCTGGCGTTGCAGTACAG CACCCTCAGCAAATGCGATCACACTCTGTCTCTTCCCAGATACCCTCTCCTCCCCTGCAG GGCGGCTCCTCCCTGGGGGCCTTTGCATCTGGGAATGGAGAATGGGGGCAGCTCATGGGG CTTTCTCCCTTCAGAAATGAAGCCACTTATTCCCAGTAAGGAAGCTGCGTGGCCAGGCTC CGGCGGCGACCCTAGTCCCACTGCACGGCCTTCCTAGTGAGTCTCGGCTCCAGGACCCCT GCTGTGCTTTAGCCCGAGCTGCCCCCACCACAAGCTAGGACCACCCGTGGCCTTCCTGCT CTTGCCCATTTCCTTTCCCCTTCATTCTTTTTTCCTTCCCTGTCTTTTCTTCAGCCTCTT AAAATTTCCACCCACCCCTCCAAACCCTCCCTCCTAGAAGGCAGGGAATCGTGTCACATG GGATGGGTTTGGGGACTAAGAGGTCCCTCATGTACTTGGCAGTAGCATTTCCTGATTTGG TGGGGATGAAAGCAGAGGATTAGAAGAGAGGGCGGGAGTAAGAAGGGAGTGTTCGAGTAT GTTTCTAGATGGGAGTAAAGGAAGCCATGTGGTGGGGTGTTGTGGAGTGCTCAGGGCTTC TGGAAAGGCAGGGGGATAGAGGAGGGTCTGGCAGGTGCAGGAAAGGGGATAGAGGAGGGT CTGGCAGGGGCAGGAGAGGGAGCCGAGCACACGTGTTCTTTCCTGGAAGGAACCAGGCTT CACAGTGGGGTGGGGAGCTGTGGCAGGGATCTGGGAGGTGGGTCACAGCTGGCCACTCCC CACCCCCAGGTTCTTGATGCTGTTCTGCCCGTCATGAACAAGGCCCATGGTGGCGAGAAG ACCGTGTTCCGGGCCAGGTTTAGCTCCATCACGGACACAGACATCTGTAATGCCATGGCC TGCCTAGGCGAGCCTGACCACAACGAGGCGCTCTCAGTGGATGCTCGCCAGGAGCTGGAC CTGCGAATCGGCTGTGCATTCACCAGGTGCTGGCCACACCCGCAGAGTCCTGGGCACACC CTCACTCTCCCTCAGCCAGAGACCTGCCTCTACTGGTCCCCCTCCGGGGCCCCTAGGCCT CCTCGAGCCAGGATGAGCAACAGGGGATTTCACCAACCCTGAAGAAGGCCAGGCACAGTG GCTAACACCTGTAATCCCTGCACTTTGGGAGACCAGGATAGGAGGATTGCTTGAGGTTGG CAGTTTGAGACCAGCCTGGGCAGCATAACAAGACCCCATCTCTACAAAAAAAAAAAAAAA AAAAATTATTTTTTTGAGACAGAGTCTTGTTCTGTTGCCTAGGCTGGAATGCAGTGGTAC AATCTCAGCTCACTGCAACCTCTGCCTCCCAGGCTCAAGAGATCCTCCTACCTGAGCCTT CCACTACAGGTGCTACAGGTGTGCACCACTATGCCTGGCTAATTTTTATGCATTTTGTAG AGACAGGGTTTTACTGTATTGCCCAGGCTGGTCTCAAACTCCTGAGCTCAAGCAATCTGC CCACCTTGGCTTCCCAAAGTGCTGGGATTACACATGTGAGCCACTGCGCCCAGGCTAAAC AAAAATTTATTTATTTTTTTGTTTGTTTGTTTTTTGAGACAGAGTCTTACTCTGTCATCC AGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGT GATTCTCATGCCTCAGCCTCCCAACTAGCTGGGATTACAGGCTCCTGCCACCACTCCCGG CTAATTTTTATACTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAA CTCCTGACCTCAGGTGATCCGCCCACCTCAGCTTCCCAAAATGCTGGGATTACAGGTATG AGCCACTGTGCCTGTCCAAACATTTTGTTTTAATTAGCTGGGTGTGGTGGTGTGAGCCTG TAGTCCCAGTTACTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGGAGTTCAAGGC TGCAATGATCTGTGAATCCCCATTAATGCACTCCTGCTGGGCAATACAGCAAGACCCTGT CTCTACAAAAACAAAAGAGACCTAAAGAAAATTGTTTATTTAGCTGACAGAGATCACATA TGCCCTGCTTGATAAAGTGTGTTTGTCTGTGCTCTGGGGGTCCTGAGGAGAGTGTGCAGT AGATGGAATAGAATAGAAGGCTCCCTGGCCTGAGACAGTAGAAACCTCTGTCTCCTCTCT CACTGGCTCTGTCACCCATGTACACACATGAATCCTCCCTAAGGCTATGCCCACTCTGCT CCCACTGGCTTCTAAGTGGGGACACCACCTGATGCCACCTCCTTCATGCACCACCCCTGG CCTTGGGCTGGACTCACATGGGTGGCCATAATAGTGTCTTGAGTGAATCAGTGACCAAAA TATCTTTCCACTCCCTCCAGGTTTCAGACTAAATATTTCCAGGGGAAATACGGTGATTTA GACAGCTCTCTCATCTCCTTTGGGCCGTGTCAGACTCCAACCCTGGGATTCTGTGTGGAG AGACATGATAAAATCCAGTCCTTCAAACCAGAGACCTACTGGGTGCTGCAGGCCAAGGTT CCTTGCCTTTCTCTATTCATGCTGGGGCTTTCTGGGTTTGGGGCATGGATTCTGAGAGTC TTCCATCATCATCAGCCGGCAGGCCCCGGGCTGAGGGCAGAAGTGTGGACGGCTGTACCT GGAAGTGGTCTGTGGTGCCTAGGGCTGAGGGACCCCAGCCTTCATGGGGGCAGTGGGAAG AGACTGGGCCTGTATATGCTGAATCTGGATAAGTGGGAATGAGTTCAGCTCTGGCAGTGC AGGGTGAGGTCACCCCACAGGAATCAGTGGCTTCAGTGGTCAGGTCCAAGCACTGGACTG AGACCATTGGCTTTCAAACTTTTTAAAATTCCTAGAACCCTTTCTTCAAATAAAAGCCTC CACAGAAGCTCACTGTAAGACTTAATACAGCTAGGCACAGTGACTGATGTCTGTAATCCC AACAACCTGGGAGGCTGAGGCAAGAGGATTGCTTGAGGCCAGGAGTCCAAGGCTACAGTG AGCTACGATCGTGCCACTGCACTCCAGCCTAGCAACACAGTGAGACACTGTCTTGGAGCT GCTGTGGCTGACACGGGGCTTGGGACCCTGGCGGTGGCCATACCTACCACTGGCCAGGCA CTGGGGATAGGCAGGGGTGGTGTGAGAAGTAGGGGCTCAGGTGCTTCTTAGGGACACATC AGCCTCAGCTTTGGGCCACCTTCCTGAGACTGGCTGCCTGGTTTTGGGGCAAGTGGTGGA GAGGGCCAGATGTCAGCTTGCGTATCTGCCCACCTGAACAGGTACAGCTGTGAGCCATTA CAGCCAGGGCTATTTGGCTCCCAGACAAGGACCAGCTTCATCTGTCCTGGTTCTTCCTGG CGTTGGGCTCACCTGGAGACTTTTTCTTGTGCGTTCACCCTTTATCCTTTTTCCTGCAGG TTAACACTGACAAAGACAGATCTCTCCTTTTGGACTGGGACCGAGTAAGAGTGTTTGACC GGGAGATCGCACAGATGTTTTTAAACATGACAAAGCTGGAGAAGGAAGCCCAGGTGTGCC TGCTCCACCCACATCTATCACAGTTGCCTTGGGTGAGGGTGGCCCTTGGATGCCTCCCGC TGGAGGAACAGCCTGTGATCCTAGTCCACGTCTTTCTCCCCCTTTCTGAAACACAGACAT CTTTTTGGAAAGCTGAATGGTTACTCCCTCATATACTCCTAAGATATTTCTGCCCAGTGC AATAGTCACAGTGTACTGCATGCCCGCTCCATACCAGGCACTGTCCACACCTGTGACCTT GTCGGACCCCTTCCACTCTCCCCTTTCCACGTGACCCGCTAGGCATTACCTCCGTGTGGC AGGACTCCATTTCACACAGAGATTCAAACTAACAACTGTAGAGGGACCTTGGTGCACACT GATGAACTTGCCCAAGGTCACAGCTAGCAGGGGAAAGTCTTGAGATTCCAATTGCAATCA GCTTGCGTGCTTTTATGGGATTATGTTTCTTACTCAGGGCTTCTATGAATTGAAAGGACA TGCTGCTTGGCTGTTAGGAAAACGGTGAGGTGACCTGGCTGCATGGGTTGGGGACACATC TGTGGCTATTGAAGTAAACATGCTACAGGCATGACAGCTACCAGATCCGTCGAGACACAG CCTGGCCTCCTTAGCCGCCTTCTCCTTGTCCTTCTCTGGCCTTCCTTGAGTGCCCTGTTG CCCGCCATGCTATCGTCTCAGGCATCTGAAACTTCTAAAGCTGCTCCAGGCTGTCAGCAT TGATCACATTCCTGCAGAGACACTGTTGCCACCTCCAGGCCTCACGCTGGGGAGCCCAGC TTCACATAACAACTGGCCTCTGTTAGCACCCACATCTGTCTGTCTGGAATGCAGAAGGCA CTGCCCTGACCAGCCTACGTGGGATTGGCAAGGGCCAGGGCCTGGGGTTGAGTTGTTTGG ATTGTTTTTGCCATAGGCAAAACAAAGAGTTGTCTCTTCCGACAAGTGTTCAGCAGAGGT AGAGAGTGGCAGGACCCCAACAAAGCACAGCTCATAGATGCACTCCACTAACCTGCATGG TGTTTACACAAATTCCAGAATAGTTACCAGCACTTAAAAATTACGAGATTTCATACTAAA ATTCTGCCTTCTAGCTTCTCTTGAAAAATCAGAAGAGGTAGCAATACTAGCAGGTGCAGG CAGCAGCCCTCCCCACAACAAGGAGTGGTACTTCCCCTGGGACGGGCCCCACTTGCCATC CCTGTAGCTTGGCTGATGCTGGCTTCTGTAGGATTTCCATCTGCAGCCCTTCTGACTCCT CCTCAATCTTCCAGGTTTTCTCTTTCCCTAGAAAATTCTCCAGAAAAGAATATTCAATCA CTTGAGGCCAGGAGTTTGAGACCAGCCTGGACAACACAGGGAGACCCTGTCTCTGAAAAA AATAATTTAAAAAGTAGACGGGCATGGTGGCACGTGCCTGTAATCCTAGCACTTTGAGAA GCTGAGGCGAGAGGATTACTTGAGGCCAGGAGTTCATTTAAGACTAGCCTGGGCAACATA GCAAGACCCTGTCTGTACAAGAAATTGAAAAAAAAAATTGGTCAGACATGATGGTGTGTG CCTGTGGTTTCAGCTACACAGGAGGCTGAGGCAGGAGGATCACTTGTCCCAGGAGTTCAG GGCTACAGTAAGCTCTGATGGTGCCACTGCACTCCAGCCTGGGCGACAGAGCAGGACCCT GTCTCTTAAAAAAAACAAAATTTGGTTTTTTGTTTGTTTGTTTGTTTGTTTTGAGATGGA GTCTTGCTCTGTCACCCAGGCTGGATTACAATGGCGTGGTCTCAGCTCACTGCAACCTTC ACCTCCCAGGTTCAAGCAATTCTGCCTCAGCGTCACGAGTAGCTTGGATTACAGGCACGT TCCACCATGCCCAGCTAATGTTTGTATTTTTAGTAGAGACGGGGTTTCACCATCTTGGTC AAGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTACTG GGATTACAGGCGTGAGCCACCACACCCAGCCAAAATTTTTTTTTAAAAAAGAATTTTCAT TCTTTTTCCTTTCCTGGTCCTGAATAAATATTCAATCAAGTCTTTAGACTGTTGGGAAGA ATGAATTGGAGAAACAGGGAGACCAGATGAATGAAACCAGACCCTTCGTCCACACATCTT GATTCCCTCTATGGTGGTGTCTTCCTCCTTCCCCAAATCATTGACTGTCCTGTCTTCCAG GTGGAGGCCACAAGCAGGAAAGAAAAGGCCAAGCAGAGGCCCCTGGCCCTGAACACTGTG GAGATGCTGCGTGTGGCCAGCTCTTCTCTGGGTATGTAGGGACATTTCTCTCAAGTCACC AGAAGGCTTCCTGAGGCAGGTTCAGCCTGGAGCAGCGAGTGCCCAGGGTTGCAGGATGGT GCCCAAGGCTTCAAGGGGATCTGAGCCTCAGGAGGATTTCACTTATCCTTAGGTTGTAAA GGTGGTAAAGTTGGTCACCACCTGAGGGGACCTCCTGATGTTAGAGTCCCTGAGCAGCTA TCCCTGGTGAGGGGAGAGGCCCCAGCCAGATGTCACCTTCAGGGAACCAGTGTGAACGTC GCCCCTCAGCCTCATCTCCTCAGTCTTTTCTCCTTAGTAACGAGGAGGGGGTTGGGCTGG AAAGCTGGTGGTCTCTGGCAGCTGTCAGCCCCTAGGCATTGGTGCCCCCCACCCCCGCAG GGAACTATGGGCAGTGTCCTCTCAGTGGACACTGAGTGGTGGCTCCAGCGTCCTCAGAGG GCAGCAATGCTGGGAGTGGTTGCTAGCTAAGCGCCTGCCTCTGCTGGTCAGGGAGTAGCA GGACGAGCCCCCCTGAGTGGCCCCAAAGTGCTGTGAGGACAGAAACACCCAAGGGCTCAA AATGGGGCTGCGTGCTAACTCTGTCGTCAGCCAACCCCGAGGTATGGTTATGGCTCCATG GACAATGCATGGGGAGTGGTGCTCTGAAGGCCATGTGTCATCCCCATGGCCATGAGCCCC ATGAGGATGCACCGTGGGGTAGAGTGAGTGGCGTTTCCCATCAGGCCCATCCTGGGTGTA GGATTCAGCCTTACGGGTGCGGGATTCAGCCTCATACAAGACTGTGTGGCATAGGTGCCC ACCCGGCCAGCAGCTTTGCACTCCAGCTGTGCCTGCTCAGAGCCACCGTCACCCTCCAGG AGGGGCCGGCCACAATGGGGGAGCCTGAGTGCATAGGCCAGGGCAGGCAGCTGGCCATCC CCACGTACCTGGCCCTCTGAGAACCTCCTGTCTCTCGCAGGCATGGGGCCGCAGCACGCC ATGCAGACGGCTGAGCGGCTCTACACGCAAGGCTACATCAGCTACCCACGGACAGAGACC ACCCACTACCCTGAGAACTTTGACCTGAAGGGCTCTCTGCGGCAGCAGGCCAACCACCCC TACTGGGCCGACACGGTGAGTGGAGCCGGGCCGGCCTCAGCATGTGTGTGTGTCACTGAG GCCTTGGGACCAGGTCTGGTACGTCAGCCAAACCCAGGCAGGCAGCCGAGCCCAGCCACA GACTCTGCTCTGTCTTCTCTCCCTCAGGTGAAGCGGTTGTTAGCAGAAGGTATCAACCGC CCGCGGAAAGGCCATGACGCCGGCGACCATCCCCCCATCACCCCCATGAAGTCTGCCACA GAGGCCGAATTAGGTACCGCTCTCATCCCATACCCGGTGTGCTTCCAGGGAGGGAAGGGC GAGCTGCGACAGTGAAGGTTGCAGGCCCTGTTGGCAATGTGGGGGCTCCTTCAGCCTCTG CCTGCCCTGGCTGTGGGGATGGGGGGCCACCTGGAAGATGAGCTCCATTGCTATGGGACC AGGACAGGAGTGAAGAGGTAGCAGCAGGTGCTGTTGCAGGGAGGCAAGGGGGCAGACGCC ACAGGGGACATGAATGAAACCAGGGTAGAGAGTGGCGGTGTGGGGGAGGGGGCAGCACAC CTCCTACCTCCCAGCTGGCCTAAGGTGGTACCAGTGGTCCGAGTGCCAGGAGAAGGCAAA TGAGGAAGGGAGAGCAGTGCAGGTAGAGACAGGAGCCACCTGTGGACAGTCTGAGTTTGA AGCAATGGTGTCATGTCACGAGACAATGGAAAGACAGGCCAATGCCTGAAGAGCAGTCCC GCCAGAAGCAGGGACAGGAGGTTGTGCAGGATGGTGGGAGCCGCAGCCAGAAAGAAACCA CTGAGGCATGGAGGCTTGTGTTCCCTTCCTCCGCATTTGCTTTTTTTTTTTCTTTTTTTG AGACAGAGTCTTGTTCTGTCACCCAGGCTGGAGTGCAGTGGCCCGATCTCGGCTCACTGC AACCTCTGCCTCCCAGGTTCAAGCAGTTCACCCTGCCTCAGCCCCCCGAGTAGCTGGGAT TACAGGCTCCCACCACCACACCCAGCTAATTTCTTTGTATTTTTAGTAGAGACGGGGTTT CACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCATCCACCTTAGCC TCCCAGAGTGCTAGGATTACAGGCATGAGCCACCACGCCCGGCCTTCCTGCACATTTTCT TTCCTCCTTCCCCAGGATTTGCAGTGTGTCCTGCACAGCGGCTCTGTAAGCAGGAGCTTG CTGCTCGAGCGAGAGTACTGGGGGCTCCTCACGGCCAGAGCCCCCAGCTGGCTCCCAACT GACTAGCCCTGGCCTGTTGCAGGGGGTGACGCGTGGCGGCTCTATGAGTACATCACCAGA CACTTCATCGCCACGGTCAGCCATGACTGCAAGTACCTGCAGAGCACCATCTCCTTCAGA ATTGGGCCCGAGCTCTTCACCTGCTCCGGGAAGACCGTCCTCTCACCAGGTCACACCACG GGCCCAGCCTTCCTCCTCTGTGCCTTCATGGGCAGACAAACATTCTACATCGTGTCTGGG GATGGGAGGCCCAGGGTCTGAGGCCCCGGCCACCCAGGCTGGGGACCCTGAGTGGCGGCG CATATCTCTCCAGGCTTCACGGAGGTCATGCCCTGGCAGAGCGTGCCCCTGGAGGAGAGC CTGCCCACTTGCCAGCGGGGTGATGCCTTCCCTGTGGGCGAGGTGAAGATGCTGGAGAAG CAGACGAACCCACCCGACTACCTGACGGAGGCCGAGCTCATCACGCTCATGGAGAAGCAT GGCATCGGTGGGTGCGCCTGCCCAGGCCCCAGAGCCGGCTCCGTCTCCAGTACTCAGGCT TCGAGTCTACTCACAAAGCTGCCCCGCCAGCCCTGTGTGCCCAGCCCAGCACCCCTCCAT GGGCTGGTATCTGGAAACTGGTGACCCAGTGTGTGGCCAGCCAGGCAGGTCCACAGCGGG CATCCCCTCCTGAGGCCTCCATTCAGGACCTGGCCTTCCCTGTGAAGGCCCAGATGTGCC CTCGTGCACTGTGGGGTGTGCACACACCGACTAACGCCCACAAGGCTGAAGATTGGCCCA GATGCCAGGTGACTCATAGAAATCATATTGGCAGTCCCCTGAGTCCACACAGCCAGCCTG GGCTGTCCTGAAATCAGGTGACAGGGAAATGAGATCTCACAGGAGCTGCTTCCCTGGGAG AGAACAGAAATGCCTGTCCCAGGCACAGGGCTCCCCAAAGGGTGACCAGGAAGTTTCCAC GCAAAAATGGGCAGCCCAGGGAGTTTATCAAAGCAAAAGTGTAGTCACCAGTGCACACTC CTCACAGGAGTGGTGGCCTCACAAGTCCCCAGGCCTGGAGCTGTGAGATGTCTCACATGT TGGGGGCCAGCCTCACTGCCGGAGCCTTCTCCCCAGGTGGCACTCGCGCCGCTGGGCACT GCCTGTTCCCTGGGGCACTACCCCTGGCTGACAGGCTCTGGAGACCTGTGGGATGTCACA GCCACTGTGTCCAGGCTCTGCTCCAGCAGTGGTCATATAGGTGGACTCTCAGGGAGTGTC TCTTCCCAGGCTGGGGTCCTGGTGACCATGGCGATCTTGGCAGGAGAGCAGAGCTCTGGG CTTGCTCCTCTCAGGGGTCCAGGGCACCTGCCAGGGTCCTGAAATAGCCCTCAGCCCACT GTGGAGTGTGGGCTCTGCTCCCCCGTGTCCTCTGCCCTCTCGCATTGATGGGACACTGGC TCCTGGCAGCCCTATGCTAGCCAGTGAGCCAGACCCAATCACCAATACAAGTTTGTGACA GTGAAGAGGGCTCTGGTGTTACCTTCTGAACAGGAGAGTGGTCAGGGTGGCCCTGTGACT GAGCCCCCAGGAGTGTGTCAAAAGGGCCTGACCAGAGCCGCCACAGAGGAGCCCACACCA CGCGTCATGGCGCCCGGCAGACTCGGGGTGGTAGTGGCACACGCCACCCACAGCCTGCCA CACCGGGTGCAGAGCTGGCCTCGTGCCAAGAGCCATGGGCCCTCGGCAGGCTCCTTAGCC CCCAGAGGCCAGTTTCTTCCCATGTGAGATTCTCTCCGAGCTACTTTGGGAAGGTGTGTG TCACCTGTCCATGCTGGTGAGCATGCAGGGAGCCCCAGCCTCCTTTCTGCCCCTCTGACT GGCACCCGCCATAGTCAAAACGCCTCAGCCTCCGCTGCGCCCCTCTGCCAGGAAACTTCC TCTGGGTGGGAGAGTGGAATCCTGGGGACTGGGAGCCTCCCCTGGGGATCGTGACGGGCC TTGCAGAGAGGGAGGAGGTGGGAGACAGGAAGTGGACAGAATTGTCCAGGTTTAGGGGAG GGCAGCTCTGCAGTGAGCTTGTAAGCACCTCCGTGTTCTGGTGGAGTGGGGCTCTGGCTC CGGGAGCAGGTGGGTGCCACAGGACCCAGGCAGGAGAAGCCATAGAAGTCACATTTTCCA GGCGCAGAATAAGCACTGTGACCTTGGAGAGTTCCTTAACCTCCGAGCCTGTTGTCTCTG CCATAAAGCAGGAGTAGGCGCCCTGTACAGGGAGGGCTGCCCTTGTGTTCTCAAGGCAGA ACATGAAATGCATGCAGTTGGTGCCCAGCACAGTGCAGGGGGAGCTCAGGGCACAGCCCT CCCTCCTGTGACCGGGAGCAGTGAGAGGGCCTGAGCACCAGGGGCCCCGTGACAGGTGAT ACAGCACATGGTTCAGTGGGGCATGTCCAAGGCAGGCCAGGAACCCTGGGGCCTTGTACA TTGCAGGCACGGATGCCAGCATCCCTGTGCATATCAACAACATCTGCCAGCGCAACTATG TCACGGTGGAGAGCGGGCGCCGGCTCAAGCCCACCAACCTCGGCATCGTCCTGGTGCACG GCTACTATAAGATTGGTGAGTTCCTCAGTCCTGCCCCCAGGGCCCACCGAGGCTCCCTGG CTTCTCCCTGGATGTTGGCTCTGCTGCCCGCTCCAGACAGGCCCCTGCCCTACAGTGATC CCCCAGCCCCACACACACTCCCTCAACACCCGCTGAAGGGGTGCTGCCCCAGGACCCCCA GGACCTGCCCAGAGCAGGAGCTCAGTGTGTTTGAAGGCTGAACAGATGTGTGAGGGAACC AAAAAGGGAGGCGAAGTTGCCTCAGCCCTGTTCCCTGGAGGTTCCCCAGGGGCCAAGGGG AGAGGGAGGAGCACAAAACTGGCCCAAGGGCGGCCTGGAGCTCATGTGTGATGTGGTTCT AGCCACAGGACATCCCTGGCCACTCTGCCTGACATTTCCAGGTGGGAAATCAGGAAAGGT CTGGGGTCATAAGAGCCAGCCTGGTACCATCTGAGGCTGTGGACTGGTGGGTAGGGCAGA GGCCAGGAGGACGGGCCAGAGCGGGAGGGGTGAACAGGGCAGTATCCCTGCCTGGGAAGG GGTGGCATGGCCCTGGGTGCGAGTGCTCAGGGCAATATCTGCCCCCTGCCCACTTGCAGA TGCAGAGCTGGTGCTCCCCACCATCCGCAGTGCAGTGGAGAAGCAGCTGAACCTGATCGC CCAGGGCAAGGCCGACTACCGCCAGGTCCTGGGCCACACCCTGGACGTGTTCAAGAGGAA GTTCCACTACTTTGTCGACTCCATTGCTGGTAGAGTCTGCCTCTGGCCTGCCCCTCACCA GAGGGGTGTCTCTCTGTCAGCAAGGCCAGTACCTGGGGACCCAGGTCCCCACGTGGGACC AGCTCCCAGATCTGGGCTTCAGGCCTCCGTAGGCCAGGTCAGTGACACCTCCTGGCTGGG TTGAAAGAGCAGGTGCATTAACACCACACATGGCCAGGAACACGTGCCTCTGACGCACAG GGCTGCTGCCCTGCCGTGCTGCCAGGACAGTAGAAACCACCGCCTATAGGGACCCTTTCA CACTCAGACCCTTGACCACGTGTTGCGGAGCCTTTTGCTGGGGACTGGGAGGGAGATGAC TCCTGCACTCTGCTTGCCCGCAGGCATGGATGAGTTGATGGAGGTGTCTTTCTCGCCCCT GGCGGCCACAGGCAAGCCCCTCTCACGCTGTGGGAAGTGCCACCGCTTCATGAAGTACAT CCAGGTAGGTGCAGGGAACACTAGCTCAGGCAAGCTGCCTCACCCCTGTAGGCCTCAGCT TTATCGTTGATCAGCAGGAATCATGTTCTTTGTCCTGGTTGTCACAAAAGAATGATGGAA CATAAAGAGGCCTTGCCAAAAAATACCCAGTGTCCCCACGTCCCCTAGAATACACAGCCA TTAGGCCACGCAAACACACATGGTGCATTTTTCCCTAACACCATGCCACTTGCCATCATG GGCATTAATGTACACACAGAGATTTTAGAACTGCCTTTTCTGCACGCGTGGAGCAAGAGC CAGAGACTCATGCTCCTTGCCTGGCAGTGTGTCACAGGTTCTGCATGACAGATTACATAC TTTGTATTATGAGAGGAGTGGGGGTGGGTGCCAAGTCGGTGGCCCCAGTGACCCTCACGC CACCTGCCTGGCATTGCCGCAGGCCAAGCCAAGCCGCCTGCACTGCTCCCACTGCGATGA GACCTACACGCTCCCCCAGAACGGCACCATCAAGCTCTACAAGGAGCTCCGCTGCCCTCT GGATGACTTCGAGCTGGTCCTGTGGTCATCAGGCTCTCGGGGCAAGAGCTACCCGCTGTG CCCCTACTGCTACAACCACCCACCCTTCCGAGACATGAAGAAAGGTGAGTGCAGCCACTC CCTCCTGTCCACAGGTAGCTGCAGTCTCTTTTCAGTGCCAACCCCTGCCTTGCACCAGGC TGGACTCTGAGGGGACCCCTCACCCTGGCCTTTCCTGCACTCATTGGCACTGAGACGAGA GACCCTGGATGTAGCTGGGGCACTGCTTAGGCCTCAGCCAGTGGTGCCACCCTCTCTCTG TGTCAGAATCGAGCAGGCAACCCTAGTCCACCCTCAGGACCTGGGCACAGGTGTGCAGTG CTCCCTCTGGAGCTGAGTGAGCAAGAGGATGCAGCAGTCGGGGGACCCACCCGGTGAGCG GGCACCCCCAGTCAGCGTCCACCACCGTCCTCCATCCTCATCCTCGTCCTCATTACTGGA GGAGGGAGCGCATGTCCAGGCAGGCAGGACAGAGCACCGAGCCAGACCAGGAATCAGCGG GAGTGAGGCATCTGCCCACATTCACCGTGTGCTCTGCAGAAAGCTCCCTCAGGCCTCAGT CTGCACCCAGGCTGCCCCGGGAGTGAGACCCCATCCCTGCCCTCCTGCTGCCGCCAGAGT AGCTGACAGGGTGGTTCCATGTGGCCCAGTGACATGAGGGTCATGTGGCATTACCAGTAA CAAGCTGGCAGCAAAGCAAAGGGGGGATGGAGTCAGCTGAAACCCACTGGGATGGTGCCA GCGAGGGGCCTTGAAAGTTGAGGAGGTTTCAGGTAAGCAGAAAACAGGGGTAATGGCAGC CAGGAGCCGAAACATGAGCAAGGCTGTCCCCAAGAGCAAGGCCAAGAAGAGTTCCTTCTG CTGGGACGAGGGATCCAGGAGCTTGAGGCATTGGGAGCAGGCAGCAGAGGGCAGGTGGGC ACAGTGGGCGTGCCTTTACAGGGCTCCCTTCTCCCGCCAGGCATGGGCTGCAACGAGTGT ACGCACCCCTCCTGCCAGCACTCGCTGAGCATGCTGGGCATCGGCCAGTGCGTGGAATGT GAGAGCGGGGTGCTGGTGCTGGACCCCACCTCGGGCCCCAAGTGGAAGGTGGCCTGCAAC AAGTGCAACGTGGTAGCGCACTGCTTCGAGAACGCCCACCGCGTGCGGGTGTCCGCCGAC ACCTGCAGTGTCTGTGAGGCCGCCTTGCTTGATGTGGACTTCAACAAGGCCAAGTCCCCA CTCCCGGGCGATGAGACGCAGCACATGGGCTGCGTCTTTTGTGACCCCGTCTTCCAGGAG CTGGTGGAGCTGAAGCATGCGGCCTCCTGCCACCCCATGCACCGCGGTGGACCAGGGAGA AGGCAGGGTCGAGGGCGGGGCCGGGCCAGGAGGCCCCCTGGGAAGCCCAACCCCAGACGG CCCAAGGACAAGATGTCAGCCCTGGCCGCCTACTTTGTATGATGACCCTGTCCTCCCTCA CCCAGGCTGCAGTGCCATGCAGACACCTCATGGCACTTCAAACTATTAAAATGCATTTTA TCTTA OMIM ID 603582