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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CCNF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID899
Official gene symbolCCNF
Full namecyclin F
Aliases,FBX1,FBXO1,
Gene summaryThis gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq]
LocationChromosome: 16   Locus: 16p13.3
Gene position2479395 - 2508859  Map Viewer
Gene orientationplus
Gene size29465 bp
Gene sequence
OMIM ID600227