Entrez gene ID | | 89910 |
Official gene symbol | | UBE3B |
Full name | | ubiquitin protein ligase E3B |
Aliases | | ,DKFZp586K2123,DKFZp686A1051,FLJ45294,MGC131858,MGC78388, |
Gene summary | | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family. The encoded protein may interact with other proteins and play a role in stress response. Alternatively spliced transcript variants encoding the same protein isoform have been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24.11 |
Gene position | | 109915439 - 109974507 Map Viewer |
Gene orientation | | plus |
Gene size | | 59069 bp |
Gene sequence |
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OMIM ID | | 608047 |
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