Entrez gene ID | | 9020 |
Official gene symbol | | MAP3K14 |
Full name | | mitogen-activated protein kinase kinase kinase 14 |
Aliases | | ,FTDCR1B,HS,HSNIK,NIK, |
Gene summary | | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21 |
Gene position | | 43394414 - 43340488 Map Viewer |
Gene orientation | | minus |
Gene size | | 53927 bp |
Gene sequence |
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OMIM ID | | 604655 |
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