Entrez gene ID | | 9040 |
Official gene symbol | | UBE2M |
Full name | | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) |
Aliases | | ,UBC-RS2,UBC12,hUbc12, |
Gene summary | | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.43 |
Gene position | | 59070343 - 59067079 Map Viewer |
Gene orientation | | minus |
Gene size | | 3265 bp |
Gene sequence |
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OMIM ID | | 603173 |
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