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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSTPIP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9051
Official gene symbolPSTPIP1
Full nameproline-serine-threonine phosphatase interacting protein 1
Aliases,CD2BP1,CD2BP1L,CD2BP1S,H-PIP,PAPAS,PSTPIP,
Gene summaryThe protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q24-q25.1
Gene position77287465 - 77329671  Map Viewer
Gene orientationplus
Gene size42207 bp
Gene sequence
OMIM ID606347