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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NFS1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9054
Official gene symbolNFS1
Full nameNFS1 nitrogen fixation 1 homolog (S. cerevisiae)
Aliases,HUSSY-08,IscS,NIFS,
Gene summaryIron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q11.22
Gene position34287274 - 34256611  Map Viewer
Gene orientationminus
Gene size30664 bp
Gene sequence
OMIM ID603485