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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD1A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID909
Official gene symbolCD1A
Full nameCD1a molecule
Aliases,CD1,FCB6,HTA1,R4,T6,
Gene summaryThis gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q22-q23
Gene position158223927 - 158228059  Map Viewer
Gene orientationplus
Gene size4133 bp
Gene sequence
OMIM ID188370