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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KCNQ4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9132
Official gene symbolKCNQ4
Full namepotassium voltage-gated channel, KQT-like subfamily, member 4
Aliases,DFNA2,DFNA2A,KV7.4,
Gene summaryThe protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p34
Gene position41249684 - 41306124  Map Viewer
Gene orientationplus
Gene size56441 bp
Gene sequence
OMIM ID603537