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Gene information for CD247 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID919
Official gene symbolCD247
Full nameCD247 molecule
Aliases,CD3-ZETA,CD3H,CD3Q,CD3Z,T3Z,TCRZ,
Gene summaryThe protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q22-q23
Gene position167487847 - 167399877  Map Viewer
Gene orientationminus
Gene size87971 bp
Gene sequence
OMIM ID186780