Entrez gene ID | | 919 |
Official gene symbol | | CD247 |
Full name | | CD247 molecule |
Aliases | | ,CD3-ZETA,CD3H,CD3Q,CD3Z,T3Z,TCRZ, |
Gene summary | | The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q22-q23 |
Gene position | | 167487847 - 167399877 Map Viewer |
Gene orientation | | minus |
Gene size | | 87971 bp |
Gene sequence |
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OMIM ID | | 186780 |
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