Entrez gene ID | | 9191 |
Official gene symbol | | DEDD |
Full name | | death effector domain containing |
Aliases | | ,CASP8IP1,DEDD1,DEFT,FLDED1,KE05, |
Gene summary | | This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23.3 |
Gene position | | 161102478 - 161090767 Map Viewer |
Gene orientation | | minus |
Gene size | | 11712 bp |
Gene sequence |
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OMIM ID | | 606841 |
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