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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DLG5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9231
Official gene symbolDLG5
Full namediscs, large homolog 5 (Drosophila)
Aliases,KIAA0583,LP-DLG,P-DLG5,PDLG,
Gene summaryThis gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q23
Gene position79686348 - 79550549  Map Viewer
Gene orientationminus
Gene size135800 bp
Gene sequence
OMIM ID604090