Entrez gene ID | | 9348 |
Official gene symbol | | NDST3 |
Full name | | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 |
Aliases | | ,HSST3,MGC130028,MGC130029, |
Gene summary | | This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q26 |
Gene position | | 118955500 - 119179789 Map Viewer |
Gene orientation | | plus |
Gene size | | 224290 bp |
Gene sequence |
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OMIM ID | | 603950 |