Entrez gene ID | | 9377 |
Official gene symbol | | COX5A |
Full name | | cytochrome c oxidase subunit Va |
Aliases | | ,COX,COX-VA,VA, |
Gene summary | | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q24.1 |
Gene position | | 75230495 - 75212616 Map Viewer |
Gene orientation | | minus |
Gene size | | 17880 bp |
Gene sequence |
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OMIM ID | | 603773 |
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