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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NRXN1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9378
Official gene symbolNRXN1
Full nameneurexin 1
Aliases,DKFZp313P2036,FLJ35941,Hs.22998,KIAA0578,PTHSL2,
Gene summaryNeurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p16.3
Gene position51259674 - 50145643  Map Viewer
Gene orientationminus
Gene size1114032 bp
Gene sequence
OMIM ID600565