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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DDX23 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9416
Official gene symbolDDX23
Full nameDEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Aliases,MGC8416,PRPF28,U5-100K,U5-100KD,prp28,
Gene summaryThis gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q13.12
Gene position49245957 - 49223539  Map Viewer
Gene orientationminus
Gene size22419 bp
Gene sequence
OMIM ID612172