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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MED23 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9439
Official gene symbolMED23
Full namemediator complex subunit 23
Aliases,ARC130,CRSP130,CRSP133,CRSP3,DKFZp434H0117,DRIP130,SUR-2,SUR2,
Gene summaryThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q22.33-q24.1
Gene position131949363 - 131895106  Map Viewer
Gene orientationminus
Gene size54258 bp
Gene sequence
OMIM ID605042