Entrez gene ID | | 9440 |
Official gene symbol | | MED17 |
Full name | | mediator complex subunit 17 |
Aliases | | ,CRSP6,CRSP77,DRIP80,FLJ10812,TRAP80, |
Gene summary | | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q14 |
Gene position | | 93517405 - 93546496 Map Viewer |
Gene orientation | | plus |
Gene size | | 29092 bp |
Gene sequence |
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OMIM ID | | 603810 |