Entrez gene ID | | 9442 |
Official gene symbol | | MED27 |
Full name | | mediator complex subunit 27 |
Aliases | | ,CRAP34,CRSP34,CRSP8,MGC11274,TRAP37, |
Gene summary | | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q34.1-q34.3 |
Gene position | | 134955253 - 134735499 Map Viewer |
Gene orientation | | minus |
Gene size | | 219755 bp |
Gene sequence |
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OMIM ID | | 605044 |