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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTGES (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9536
Official gene symbolPTGES
Full nameprostaglandin E synthase
Aliases,MGC10317,MGST-IV,MGST1-L1,MGST1L1,MPGES,PGES,PIG12,PP102,PP1294,TP53I12,mPGES-1,
Gene summaryThe protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.3
Gene position132515344 - 132500615  Map Viewer
Gene orientationminus
Gene size14730 bp
Gene sequence
OMIM ID605172