Entrez gene ID | | 9568 |
Official gene symbol | | GABBR2 |
Full name | | gamma-aminobutyric acid (GABA) B receptor, 2 |
Aliases | | ,FLJ36928,GABABR2,GPR51,GPRC3B,HG20,HRIHFB2099, |
Gene summary | | The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. |
Location | | Chromosome: 9 Locus: 9q22.1-q22.3 |
Gene position | | 101471479 - 101050364 Map Viewer |
Gene orientation | | minus |
Gene size | | 421116 bp |
Gene sequence |
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OMIM ID | | 607340 |
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