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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RNF14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9604
Official gene symbolRNF14
Full namering finger protein 14
Aliases,ARA54,FLJ26004,HFB30,HRIHFB2038,TRIAD2,
Gene summaryThe protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q23.3-q31.1
Gene position141346437 - 141368754  Map Viewer
Gene orientationplus
Gene size22318 bp
Gene sequence
OMIM ID605675