Entrez gene ID | | 9611 |
Official gene symbol | | NCOR1 |
Full name | | nuclear receptor co-repressor 1 |
Aliases | | ,KIAA1047,MGC104216,N-CoR,TRAC1,hCIT529I10,hN-CoR, |
Gene summary | | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. |
Location | | Chromosome: 17 Locus: 17p11.2 |
Gene position | | 16118874 - 15933408 Map Viewer |
Gene orientation | | minus |
Gene size | | 185467 bp |
Gene sequence |
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OMIM ID | | 600849 |