Entrez gene ID | | 9839 |
Official gene symbol | | ZEB2 |
Full name | | zinc finger E-box binding homeobox 2 |
Aliases | | ,FLJ42816,KIAA0569,SIP-1,SIP1,SMADIP1,ZFHX1B, |
Gene summary | | The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. |
Location | | Chromosome: 2 Locus: 2q22.3 |
Gene position | | 145277958 - 145141942 Map Viewer |
Gene orientation | | minus |
Gene size | | 136017 bp |
Gene sequence |
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OMIM ID | | 605802 |