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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDK11B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 984 Official gene symbol CDK11B Full name cyclin-dependent kinase 11B Aliases ,CDC2L1,CDC2L2,CDK11,CDK11-p110,CDK11-p46,CDK11-p58,CLK-1,FLJ59152,PK58,p58,p58CDC2L1,p58CLK-1, Gene summary This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq] Location Chromosome: 1   Locus: 1p36.33 Gene position 1590473 - 1571100  Map Viewer Gene orientation minus Gene size 19374 bp Gene sequence >CDK11B:complement(1049732..1069105):Length=19374 ATACAGGAAGTGACGATACTTTTGGCGCGCGCCGGTTGCTGTTTCTTCTCTGGCTCCGGG ACCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGTAGGGGTGAGTTCCGACTGGGCGGAC CAGGTGTGGGAGCGCGAGGAGAACTGTGCACCGAGGTCTTTCTTCCGAGCAGGCCTCGGA GCGGGGCGGACCCGGGCCCGGGGGCGAGCGACACCCTCGCTTCCGCGGACAGTCTCATCC CGCACGGAACTTTGGGTGGTGGAGGCGGCGGGTCCAAACGCTGTCTGGAGCCAACGTCTG CCAGGCTGAACCTCAAGTGTGCGGGACTGAACCCGAGGAAATAGCCCAGTGCCCGGGTCA GGTGGCCTTGTTCGCGAGCACATCTCGGAGCATCTCCCCGGTCTCAAGGTGCAGCTGTCC AGTGTGCTAGTGGCTTCACGTAGTCCAAGCGGTCTTTCTAGCAGATTCTGACAGTAAAAG CAGTGTTTGATGAGTGGCAGGTCCTGAGTTAAGAGCCTTTAAACGGATGATCTTTAATCC GCGATCGATACTATCACGTAGGTGTTGTTATTCTGGTTGTACGGAAGACTAAACTGAGGT GAATTACGTTACCCAAGACCATACAAGAATGACAGAAACGAGACTTGATTTCAAGCGGTC ATTTTTCAGAACCCATCACTCTTTTTTGTCGCCCATGCTGCAGCGCAGTGGCTGTTCACA AGCGCACTTCAGCCTGGAACTCCTGGGCTCAATCGGTCTCCCATCTCAGCTTGCAGAGTA TATGGGACTACAGGCGCTCGCCACCTTGCCTGGCTTACAACTTATCATTCTTGTTTTTTT TTCTTTTTTTTTTTTTTTTTTTTTGAGACGGGGTCTTGCTGGAGTGCAGTGACGCGACCT CGGCTCACTGGAACCTCCGCCTTTCGGATTCAAGCGATTCTGCTGCCTCGGCCTCCCGAG TAGCTGGGATTACAGGCACCCGCCACCACGCCCAGCTAAGTTTTGTATTTTTAGTGGAGA CAGGGTTTTCGCCGTGTTGGCCAGGCTGGTCTTGACCTCCTGACCTTGTGATCCACCCGC CTCAGCCTAGAGCTTACCTTTTTTTTTTTTTTTTTTTTTTTAACCAAGTCTTACTTTGTT ATGTAGGCTGGAGTGCAGTGGCGCAGTCTTGGCTCATTGCAGCCTTGACCTCTCTGATTC AAGTGATCCTCCTGCCTCTAGCAGCCTCCTTCCTGTAGCTAGGAATACAGGCACGCGCCA CCACACTGGGCTAACTTTTGTATTTTTTGTAGAGACGAGGTTTTGCCATGTTGCCCGGGC TGGTGTTGAACTCCGGAACTCCAGCGATCTGCTCGCCTCGGCCTCCCAAAGTGCTAGGGT TACCGTCTTGAGCCACTGCGCCGGGCACAACTTCTTATTCTTAATGAGGATTTATTCTGA ATCCCTCAAAAGTGACTAGGTTCAAGTGTTCAGCACCATAGCTTGCTGTGTCCTGATGTA GGCTGAATTATTTTTCTTTTTGCAGTGTTTTAACTCAAATGGGTGATGAAAAGGACTCTT GGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGG AGAAAGCAGAGATAAAACGCTTAAAAAATGTAAGCCATATTTTTTAAGTAAGTGGTTTTC TTAAAGGAGATTTAATTTCTTTGCCCTCATTTTTCCATTAGAACAACGCTTCTTCGGTGA AGTTCTTTTGTACTTCCAAATGTCGCAGGTGAGCCCAAAATCTATTCTAAAAATTAACAA AAACATTCAAATATTCAGTTGACATTAAAGGCAGATTTAACACACTAAAGCTGTGTCTAG ATTGAGCATACATGGAGAATAAAATACGTTGAATGTTAAGTCATTAGCAAAACTGGACTA ATTTTTCTCGGTTCATTAGTATGTTCATAATACTATCTCTAAGTATTTTTAATATAGTGG GAACTTGCCTTGAAATTAATATAAATATTTTACATCTTTCTTGGTTTGCATGGTAATGTA CTCAGGAAACCTTTTTAGTAATTTGGTAAGAGGCATTGGCAAAGTACCTCTTTTGCTAAG ATCTTTAGCAGCATCATTTGGGATGTTAGTGAGTACAGGCATACCTTGTTGTATTGCACT TCACTTTATTATGCTTCACAGATATTGAAATTTTTCCAAATTAAAGGTTTGTAGCAACTC TGCATTGAGCATTTTTCCAATAGCATGTGCTCACTTTGTTAGCTTTTTTTTTGTTTTTGA GACGGAGTCTCGCACTGTCGCCCAGGGCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCC CAAGTAGCTGGGACTACAGGGGCCCACCAACATGCCAAGCTAATTTTTTGTATTTTTTAG TAGAGATGGGGTCTCACGGTGTCAGCCAGGATGATCTTAATCTCCTGACCTCATGATCCA CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAACAGGCATGAGCCTCCGCGCCCGGCCT TTTTTGTTTGTTTTTGAGACAGTCTTGCTCCATTGCCCAGGCTGGAGTGCAGTGGCATGA TCTCAGCTAACTGCCACCTCTGCCTCCTGTGTTCAAGCAGTTCTCCTGTCTCAGCCTCCT GAGTACCTGGGACTACAGGCACCTGCCAGCACGCTCGGCTAATTTTTATATTTTTAGTAG AGACGAGCTTTCACCTTGTTGGTCAGGCTGGTCTGGAACTCCTGACCTCAGGTGATTCAC CTGCCTCACCCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGACCT AAACCAAACTTTTATATGCGTTGGGAAACCAAAAAATCTGTGTGACTCACTTTATTGTGG TGTTTTGGAGCCAAACCCAAAATATCTCCAAGGGATGCCTGTACCATATGAGGTATCACA AAGTATTTGGTTTGCAAGATACGCCTTAAGATTCATTTTTGGCTCATATAAGCAACTAAC ATACTTGGCATAGAGTCTAATGTCCCTTGTCATATATGCTATTTTTAAATTTCTCATCTC AGGTTTCAGATTACAGAGAGTTGTAATTTTAATGTGATAAGATTTGAATTAAAGTTTGTT TGTTTGTTTGTTTTCCCTGATACGGAGTCTAACTCTGTTGCCAGGCTGGAGTGCAGTGGT GTGATCTCGGGTCACTGCAATGTCCGCCTCCCGGGTTCAAGCAGTTCCGGTCACTACGCC CAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGTTGTCCAGGGTGGTCTC GAGCTCCTGACCTCGTGATCCGCCTGCCTGGGCCTCCCAAAGTGCTGGGATTACAAGCGT GAGCCACCACACCCGGCCAAAAGTTCTTTATATTTTATAACACTGGCTCATTCAGAGTAT ATATGAAAGTTTGTTTTGGGATGTTGCCCAGGTTTGATTATCATTAAAAATACTTTTATC TATGAAGAAAAAAAAACTTATAAAGAAAATGATTAACTTTCTCTTTGCTTCTTAGTCTGA TGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACCGCATGGA GATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCTATGGAAGACAGGTGAGCGGA TGTACAGATGTGCAAGACCCAGCTGTACACAGCCCTGGCCTGGCCGGTCCTTCCTAGGGT CACTGTGACAACTGTGTGCTGTTGTAACTATTAAGGTTTACTCTTTCCTAGAGTTACTGT GACATAGCGTAACTATTGAGGTTTTTATGTCACAGTTGTGACTGACTCTCAAGTGTTGTC TGTGGCCCTCCAGACCCTTGCCCCTTCTTTCTGTAAAGAACTTTGCCATGTGTTACACTG ATTAATAAAATATACTATATAGGATTTTGCACAGGCCAGGTGTGGTGGCTCACACTTGTA ATCTCAGCACTTTCGGAGGCCAAGGCGGGCTGATCAGCTGAGGTCAGGAGTTCGAGACCA GTCTAGCCAACATGGTGAAACCCCGTCTTAAAAGGAAAAAAAGGCCGGGCGCGGTGGCTC ACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACAAGGTCAGAAGATC AAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAGAAAATTAGCC GGGCGTGGTGGCAGGCGCCTTTAGTCCCAGCTACTCGGGAGGCTGAGGCAAGAGAATGGC GTGAACCCAGGAGGTGGAGCTTGCAGTGAGACAAGATCATGTCACTGCACCCCAGCCTGG GCGACAGAGCAAGACCCCGCCTCTAAAAAAAAAAAAGGGAAAAAAAAGATTTTGCACAAA TAAAGTAGAATGCTGAAAGATACCTGAGGAGGGCCGCTGATGAGAAATGTTCATATTGGC CGGACGCGGCAGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCA CTTCAGCCCAGGAGTTCAAGACCAGCCTGGGCAACACAGGGAGACCTCGTCTCTACACAA AATAAAAAAAAGAAGATGAGAAAAACTAAATGAGTTTTCCTGCCATAGCAGGTGCCCCTC ATGGTCATCATCAGGGTTTTCAGGGCCTAGCTTCTAAGCACCCCTGACAGAGCCTAGAAT AGAGACAAGGAAATGGATGAGACTGGGGTAACAGAGCAAGACCCTGTGTGGAAAAAAAGG AAATGTTCTTGTTGAGACCTGTGTGTTCCGACGTTTCTTCCTGTGCCATGAACTGTTTCT CGTTTGTTTTCTTCTCATATCTAGCTCGTATCCGTCATCAGGTATTAGTAATTAAAGGAA ACACAGCCAGAAATTATGGTATAATGGTTTTCCTGAGAAGCTTAAGGTGTGAATTTTCCC AGAATTTTGGTGATACAGAAATCAGCTGAAGATACTGTTAAATGACGCTTTGAGATTATG AAGATTGTTTTGTTGTTGTTGTTGTTGCTTTGACACAGAGTCTTACCCTGTCGCCCAGGC TGGAGTGCACTGGCATGATCTCGGCTCACTGCCACCTCCAGCTCCTGGGTTCAAGTGAGT CTCCTGCCTCAGACTCCTGAGTAGCTAGGATTACAGGCATGCGCCACCACGCTCGGTTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTAGTAGAGATGGA TTTCACTGTGTGGTCACACTGGTCTTGAACTCCTAACCTCAGGTGATCTACTTGCCTCAG CCTCCCAAAGTGCTGGGATTACTGGCGTGAGCCACTGCACCCAGCCAAAATTGTAGGATC TTTTAACAGATTTATTGGGGAATAAATAACATAAAATGAGCTGCCCTTGTTTAAATATGA TGTGAATGGCTGGGTGCAGTAGCTCGCGCCTGTAATCCCAACACTTTGAGAGACTGAGGC AGGTGGATCACCTGAGGTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAAAGCCCGT CTCTACTACAAATACAAAAATTAGCCTGGCATGGTGGTGTACACCTGTAGTCACAGCTAC TCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAAAGGTTGCAGTGAGCCAA GATTGTGCCTCTGCACTCTAGGCTGGGGGAAAGAGCGAGATTCTATCTGAAAAAAATAAA AATAAAGCCGGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGG GTGGATCATGATGTCACAAGTTTGAGACCAGCCTGACCAATATGGTGAAACCCCGTCTCT ACTAAAAATAAAAAAATTAGCCGGGTGTGGTGGCGCATGCCTGTAATCCCAGCTACTCCT GAGGCAGAGGCAGGAGAATTGCTTGAACCTGGGACTGGAAGGGGAGGTTGCATTGAGCTG AGATCCCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAA GAAGAAGTCACATTTGGTGCAGAAGTGGTAGACATGGAAACAGCACAGTGAACGCTGGAC GAGGCTGACCAAGAGAACTGTCCTGAGGGAGTGAGTTTTCACTGCATCTGGAAGTAAGAA CGGGTGTGATTTGATTGAGGGAAGACAATGAAGGGATCAGAAATCTGCATGTCCGGCCGG GCGCGGTGGCTCATGCCTGTAATCCTAGCACTTTAGGAGGCTGAGGTGGTTGGATCCCTT GAGCCTGGACGTCAAAGCTGCAGTAAGCTATGACCATGCTACTGCACTCCAGCCTGGTTG ACAGAGTGAGACTGTCTCAAAAAAAGGAGAAGGGAGATCCTAAAAACCTTGAAACACTCT GGAATTCGGGACCCTGGACTCCCAGGACTCCTGGCCATTAGTTTATATATTCGTTCCCCT TTATGAGCCAGATTCCCAAGAAAGAACATCGGTGTAGCCCCAGATCTGTTCTGTGAACCA GGAAAAAGGCTGTAGGCCAGGTGGGAGCAGGCCCATCTCCGCCTTCAGAGTGAGTCCACA GAAAGCTTGCAAGCTGCTCCAGGAAGAGAGGAGTCTGAAGCGGAAGGGCGTGTGCAGCGA TGTTTGCCAGCAGCCAGGGCTGGGTACACAGCATGTAAAGATGATGAGAGGGCGCTGGTT CTTGTTGATGCCGAAGGGTGTGGGAGACACTGAGGCCCAGGGGTCAAGGTCCGAGACCGC TGCGGGGTGAGCAAGGTTTCAGTTGGCCTAGTTCCTGTTAGTGTGTGAAACATTCATGTA TGCCACACCCTGTGCCAGACATTGGTGTGTCTTGTCCCACGAGAGTACAGCTTGGGATAG AAGTGGAGGTTGGTAGATGAAATTTGGGCTGTCATATTGATTTCCCAGAAGGTAAAGACA GGAGAGTGAATGAGCAAAAATTGTTGGGGGCAGACTTCTGGGTAGGGCCGATTCAGATCA GCCAATCCAGAACTGGGTATGGTAGCATATGCTACGTGGGAGGCTAAGGCCAGAGGACCG CATGACGCCAGCCTGGGCAACGTAGGGAGACCTTGTCTCTGACAAAAAGGAAACTGATAA GGATAATCTGAGAAGCACTGATGCTTGGAAAACTGCTGAGCTGTGGGTGAAAGCAGTAAG AATCTGACCTTCTGGCCTGAGAGCTGCTCCCTTTACTGCTTCCACTCTGCACTTGGGAAG CACGGAGGTTCCACTGGGACAGGGCAGCTGCAGGACCTGCAGTTTCCTTGCTGCCTTGGA AGGGGTTACTCCGTTTAGAGCAGTGGGCAGTGGCCTTGCCCACCAGCATCCTCAGTGGAG GGAGGAAGAAAAGGCCAAGAGGTCTGCTAGAATGAAGTACAGTGTGGTTGGGAGCAGCTG TGATCTCGCCAAAGACGTGCAGCAGAGACTGGAGAGAGCTCGAGCCGCCACCCACTTGTG ACCAGCCCTGAGGATGCAGCTGCGTGAAAGGACCTGGCAGAAAATAGAAGCCGCCACAGA TGCGAATGACGCCTGAACGTTCAGTGTGCTCCCTGTCCACACACAGCCGTGGGCCAAGGA AGCCTTACTGTGCTCGAGGTATTTGAGCCCAGCCTTTTTCCAGTGCTGGCTAATTGCTAA GCTGTGCAGCCATGGTGGTGACCCCTAGGAAGCCAAGGTTGAAAATTAAAATAGGCATGG GGGAAGGAACGGGGTGGCCACGAGCTGTGAGGGAGATGGATTTCACGGACAACCAGACAG GCCTCGGTGGTAACAACGAAAGGGAAAACTTAGAATCCAGAATTGCTACAAATGTATTAT CTAAAATACAAAGAAGTATGACAGTGTGACCCATACTGAGGAAGAACATCATCAGTAAAA ACTGTCTGAGTGTCCAGATGTTGAATTTAGTAAAGGCTTGGAAACAACTTGTGGATGGAG CAGTAGAAATTATCCATTCTGAAGAACAGAGAGAAAAAAACAAGAAAAATGCACAGAGCC TCAGAAACCCGTGGTACAACATCTGCTGTACCAAAGCACGTCGAATGGGGGTTCCAGGAG AGAGGAAAGATATTTGTTACAATAATGGTTAAAAACTTTCCAAATTTTAATTAAAAAATA TGCACATTCAAGAGCACAGGAAGTTTGAACTAGAATAAATGCAAAGTCACATCATAGTCA AACTGGCAAAGGCCAAAGAGAAAATGTTGAAAGGCCTCAGAGAAGAATGACCCATCCCAT GAAAGGGGAGCTTCAATACCGCCAGCCACTGACTTCTTAGAAACAATGGAGGCCAGAAGG CAGTGGAGTGGCATACTCAAGCTGCTCAGAGAGAAGAACCATCAGCCAGGAATCAAAACC GTTCTACACAAGTGAAAGGGAACGAACAACATTCCCTGAGAAGCAGAGACTGGTGGGATT CATTGTTGGCGAAACCTGCCTTAAAGGAAATACTAAAGGAAGACCTTCAAGTTGAATAGA AATGACACCAGACGGTAACTTGAATCCTCAGGAAGGAAGGACAGGCACTGCAGATAGCAA GTGTAGGTTGACGTCAATATCCTGTAACTATCTCTCCTCACATCTTAGGTTTTACTGGAA CTACGATTGTATAAAATAATTACACTGTTGTCATGGTATGTGGCATAAATGGACTGCACA AAGAAGACAGGGAATAAAGCTGTGTTACAACAGTTTTATATTGTACTGGACTTGAGCTAG TATCATGAGGCATACGGTGATCCCTAGAGCAACCACTAAGAAAGTTGTTTTCTTAGTGTT TTAAAAAGTACAAATAAATTAAAATGGTATGCTAAACATATGTAATTTAAAATCAAAAAG GGAAGAATAAAAAAGACACAACAAAGCAAGGAAAGTAAATCCAACTGTACGTGTAATTAT ATGACATATGAAAGGTCTCTGTGCCCCAAACAGACGGGGCAGATTATCAGATAGAAAAAC AAGATCTAACTGTATGCTGTCTGCTAGAGAACAGGAAAAGACGCAGCGTACAAACATCAG CTGTCATAGGAGAGCTTGAATGGCTGTACTCATACCAGACAAAACAGATGTTAAGAAATA TTAGAAACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACAAAAATCACCTGGGTGTG GTGGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTCAGGTATGAGAATCACTTGAACT CGTGAGATGGAGGTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAA ACCAAGACCCTGTCTCAAAAAAAAGCTAGAAACAAGAAGGAGCAAGGACTTCACAGCCAG AAACAGGCCAATACAGCAGGAAGATACAGCAATGATACGTGTGAATGCATCTAACCACAG AGCCCAAAATCCATGAAGCAAACACCGATCGAATGGAAAGAAATGGATCATTTATTAATT AGAATTGGAAATGGCAGCTGGGCACGGTGGCTCGGGCCTGTAAACCCAGCACTTTGAAAA GCGGAGGCAGGCGGATCACGAGGTCAGGAGATTGAGACCATCCTGGCTAACATGGTGAAA CCCTCGTCTCTACTAAAAATACAAAAATTAGCTGGGAGTACAGGGCGCACGCCTGTAATC CCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTCGAACCCGGGAGGCGGAGGTTGCAG TGAGCCGAGATCGCGCCACCGCACTCCAGCCTGGGGGACAGATGAAGACTCCGTCTCAAA GAAAATAAAATAAAAAAATGAAAAAAAAACTTCACGGATTGAATTACGTAGAAAGCCAGT TTACAAATGTGGACAAAAACGCGATAAGCAAGCTTCTGTTTAGGGGGAATGATGGCGTGT GCCTCTTCAGGGACCGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGC GGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGC GCAAGGAGCGGGAGGCCCGCAGGGAAGGTAGGCGGCGCGGTGGGCAGCTGTGCTCGGCGG GACGCGTGTCTGCTGCCCCCTGGTGCTGGGCACTTGCTGTCACAGGCGGGCGCTTGGTTC CGGTGCTTGCTTTTCGCCCCTGCCTTTTTTTTTTTTTTGGAGGCAGAGTTTTGCTCTTGT CCCCCAGGCTGGAGTGCGGTGGCGCGATCTCGGCTCACTGCACCCTCTGCCTCCCGGGTT CAAGTGATCCTCCTGCCTCAGCCTCCGGAGTAGCAGGGATTACAGGCACCCGCCACCATG TTCAGCTATTTTTTTATATTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGAATAGT CTCTTGATCTCTTGGCCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGCGATTACA GGCGTGAGCCACCGCGGCCGGCCAGTACGAGCTTTTATAGTCACCCACGTCCTCACCTTA ATGGAGATCTTTATTTCTTCACCCAGCTTCCGGTTTCTGTCTCGCGTCCTTTCCTTACAC CCCACACAACTCCCTGGAGCTTATTCTTCAAGGCAGGTCTAGGTCTAGTAGTAATGAACT CCCTCTGCTTTTGTTTATCTGAGAATATCCTCATTTCTCCCTCATCTTTGAAGGAAAGTT TGCTGGATACGTGGTTCTTGGTTGACAATTTTGTTGTTGTTGTTTTGAGACAGAGTCTTC TTCTGTTGCCCAGGCTGGAGTGCAGTGGAGCGATCATAGCTCACTGCAACCTCGAACTCC TGGGCACAAGTGATCTTCCCACCTCAGCCTCCCGCGTAGCTGGGACCTACAGGCGTAGCG TGTGCCACCACACCTGGCTCATTTTTCAGTAGAAACAAGGTGTCCCTGTATTGCCCAGGC TGGTCTTGAATTCCTGGGCTCAAGGAACCCTCATGCCTAGCTGACAGTTTTTCCTTTTCA CTTGGACTATTTCAGCCCATTGTCTTCTGGCCTCCAAAGTTTCTGATGAGAAATCTGATG ATCTTATAGAGGATCCCTTGGATGCTTTAATCTGATGACCTGATTGAGGATCCCTTGGAT GCTTTGAAGATTCTCTTTGCCTTAGGCTTTCAACTGTTTAATAATGGGTTTTCCTGTGGG CCTCTTGACTTCATTCTACCTGGAGTTCACTGAGCCTCTCTAATGTTTATATTTACGGTT TTCATCCAATGTGGGGGTTTTGAGGAATTCTTCAGATACCCTCTCTGCTCCTCTCCTCCC TCCTGGGCTCCCACAGATCTGTTGGGGTCCCCGAGGCCGCTCAGCACTGCTCCCTTTTCT TCAGTCTCTTCTGCTTTCTTTTCCTCAGACGATGTGATTTTATTGTCTTCAGGCTCACCG ATTATTTCTTCTGCCTGCTCACATCTGCCTGTGAGTTTCTGTTGTGAATATTTACTTTTT AGTGTCTATTGTGAGCATGTACTTATTAGCTCTGGAATTTCTCTCTGGTTTCTTGTTGGA TCTTCTGTCTCTGTTGATATTTCCGTCGTGTTCACGCGTCATTTTCTTGACTTTCTCCAC ATCTTCCTTTCGTTCTCTGAGGAACTGAAGGTTAAGACAGTTCCCTAAAGTCTTTGGGAC ATCTACCGTCAGGTGATTTTCAGGAACCGTGTCTGTTGGCTTCTTTTTTTCCCCTCTGAA TGGGACATACTGTCCTATTTCTTTGTTTCTCTTGTGTTTTTCTTAGTCAAAAAAATGGAC ATTTGATTCTCATGATGTGATTCTTCCTGGTCCCCACTCAAGGGTGTGCACTTGTTGTTT TGGTTGTGCTGGGCTGTGTCTGTGGGGTCGGCCTGTTGTGGAAACTCAGGGTCTTCACGG GTCTTTTCTGAGCCTGAGCCTTTTCCTGGTCACGTGCAGCCACTTTTTAACGTTCCCGTC AATACAGATGTTTTTAATGTTCTTGTCCTGAAGTGTCTGCCTCCTAAAGGGGGAATAGAG AGAAATGAAGGGGGCAACGGGGGACGTGGTGCTCATGCCCTGGAAGTACCTTCAGCTTGG GGGTGGCCGTGGCTGCTGCCTCTTCATGCCTCTGGGGTGGGACACGCAGTCATCACACTG ACCTCGGGTGTGTGTGTCCGTCTGCCCACCTGGGTCCGGCGAGCTGCATGCAGGCTGCTG CCTGCCAGCGGGGAGTGAGGTGGGAGCCACTAATGTGCGAAGCGGTGACGTTGATTAATG AATCACAGTTTACTCTCCAAGATTCCCCCTGAAGTTGCAAACCTTCAGTAGACTCCAGAG CACCTCAGTAGTTGCACAGGCCTGATCCTGTGATGCAAGTGTTGTCTCGGTGGGGAGACT GATTCCCAGTGCTTCCTACTCCATCTTTCCAGAATCTTCTCCCGCCCCTTCCTTTTTGAC CAGTGAAGATCAGTCTAGAAGGTCCACCTGGGTCCTCGGGCTCACGGCCTCCAGGTTGGA GCTTTTTCTCCCTGGGCTTCCTGGGAGACCTCTGGCCTCTGACCCCGATGCTGTCAGCAC CCTGTGCACGCTGTGGGTGTGTCTGCCAGGTGCGGGTGTGGGAGACGAGGCAGCTGTGCC GGGTGGGGCCTTTTGAGGAAGGCAGTGCTGCTAGTGCCATCTCCCTCTCTGCCCTGCGCG CCAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGC CACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGG AAGCCAGGTGAGGCCAGGCCGGCGCCTGCGCAGAAGCCAGCACAGTGTGAGTCTTTTCTG GGGGATGTTTGGCATAAGTGTGTAGGATTCATTTAAAGCCCAGCTAAGTAACCGCTTCAG AAGAAAGTGAGAGATGTGCTGGCTGAAGTCCTCTCGTGTCGTGAGAGGGACCGTGAGTGT CTGTGTGCGGCCAGGACACAGGACGTGTGTTTATCCGCTGGGACATTCGCCACTGGCCCC GTTAGAGAAGTGGCTTCCAGCGTCTCTGGATGAGCTGGTTTCCGACCAAGCAAAGTTAAT CGTTACGTGAAAGGCACTAGTTTTGGGGTGGTGGTAGCTTGTTTGTTTAAAAACATTTCC CCAAATTCACCTTTATGGTTTATCTCATAAGTAAAAGAAGAGAAAATGGAAGAAAGGGAC CTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCC TCGTCAGGTACCTGGAACCGCCTGGCCAAGGCCTTGACCACTGCTGCCCAGGAAGGCCCA GGTTCACCCTCTGCTCTGCTGTCTTTCTACAGCGGAATCAGGCTCAGGTTCTGAGGAAGA AGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGA GGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGA GCAGTCTGCCGGTGAGGCACCGCGACGACTGTGTGAGGTGTTGTGACTTCACTATAGTGT TAGAAACCGCAGAGAAGTAGCTGGCGGGCGGGGGAGTTGAAACTCCCTTCTATCTAGGAC TCTCTCGGGACACCTCCACATCGATTCTTTTTGTTTGTTTTTTTGAGATGGAATCTTGAT CTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCTGCCTCCCG GGTTCAAGTGATCCTCCCGCCTCAGCCTCCCAAGTAGCTGGGAGTACAGGTGTGCGCCAG CACGCCCGGATAATTTTTTTATTTTTAGTCGAGACGGGGTTTCACCACGTTGGCCAGGAT GGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGCGCTGGGATT ACAGGCGTGAGCCACCGCGCCCGGCCTGCATATCCATTCTTGGGAACACTTGTTGCTTAG CTGAAGCGGAGCCCGCATCCTGCCTGTGGCAGCACTCGCCCCGGTGCTGGTCTGAGCAGA CGCCTCCTTTCTCTTGCAGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGA GAAAATGAAAACCACCTCTTGGTTGGTAAGAACCTCCCTGGAGACAGAGCCCCCTCCTTG TCTGTCTCCGAGTGCAGCAGCCCTCTCCTAAGACAGCCGGTCCTGCGCAGCGTGGGGCAC GCCAGGGTCTGGGAGGCCGCCTGATTCGTTGGCCGCTCCAGGCTGTGCCGGTGGGGCCCG CATTCCTCAGCGAGGCACAGTGCTGACCAAGGGCGTCCTGAGTGCCCAGCAGGGCCGAGG AGCTGGGAAGCCCAGGACCAGTTCCCCACAGGGGAGGCCCGTCAGATGGTGGCTCCGGGC CTGTCCCTGCAGAGCAGAGGCCTGGCCCAGCCTCCGACAGGCAGTGAGGTTATGTCCTCA GCCTGGTGGACGTGGATGTGGGCTTGTCCCCCACATGACACCCGACGCCTCCTCCCAGCT CAGCATCCGGGCTCTGTCTCAGCCGAGCCTGCCAGCACTCTTAGGCCTCGGTGCCCTGTG TCCAGGGGACGAGAGCCCAGCGCCAGCACCTCCCAGCGGGACACGGGGCAGCCCTGCCAC GCGCTTGATGCCCCCGGGGCAGGAGGAGGTTCATGATCCTTGCTTACTCCTAGCTTCGTA ATTAGGTTCAACTTTTCCAGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGA AGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGA CTATGTGCCCGACTCCCCTGCCCTGTCGCCCATCGAGCTCAAGCAGGAGCTGCCCAAGTA CCTGCCGGCCCTGCAGGTCAGGCCCTCCCCTCGCCCCAGGCCACTGTCCGCATTGGCAGT CGGAGTTACCACAGGGGCTGAGCGAAGCCTGGCCCCCGTGTTGGCGTCTGTCGCCTCACA GGGCTGCTGGGCCCACTGGGGCAGTGACGGGCGGGCACAGCCACTGGCCCCTCATGCTTC TAGGTCCCGCCTCTTTCTCATGCTGGACGGAACTGGGTGGACAGGGAGCTGCCCGCAGGA CTGCTCTGCGGCTTGAAAGGCAGCCTGGGCGTGCGGCCGCGCTGCTGTCACTGCTGCCCG AGTTGCGTCCTCCTCCGCACTGGAGAGCAGTGCCTTCCACTTGACCCCTGCGTGGGCGGG TTATGTAGGCACCAAGGCCTTGTTACCGGCATCTGTGCAGGGCTTGGATGGGGGAGCGGC TACGGGAGTCAGTGTAGATGTGTGACCAGAAGCCTTTTGCTTAGGCAGCTATCAATAAGG CAGGATATTGTTGGGAGCGATTTGGAAGGGACAAGCCTGAGAAGGTGCCAGTGGCCTCTG GGGCCTGGGAGACCGGCAGGGACTCGGCCCCCTCCTTGGTGCCTGTGGGCGGAGAGGTTC TCTCTGGCGCATGCAGCAGGCCTCTGTCGACTGCCCTATGCCTTGTGAGCGCCTCTGCCC CTTAGTGCTGCTGAGCGTAGGCGTCGGGCCACAGGCCACCCCGAGTACATGACATCCGGC CTGGGCACCGGCCCCAAGGTACACGGAGGGGTAGGTGCCCTGGCATGGGGCATCATGCTG CGCCTGGCAGGTAGGGCCCGTCCTCAGTGTCATCCTGGTACAAGCAGGGGACACATCCAG TTTGACAAAGAGACTCTTGGGATGGCTTTTTTTTTGGAGACTGGGTCTGTCTCTGTCACC CAGGCCGGAGTGGAGTGGCTTAATCATAGCTCACTGGAGCCTCCACCTCCCAGGCTCAAA CAATCCTCCCATTTCAGCCTCCTGAGTAGCTGGAACTACAGGCGCAAGCCACCATGCCTG GCTAATTTTTTTATTTTGTAGAAAGGAGTTTTGACCGGGCACAGTGGCTCACACCTGTAA TCCCAGCACTTTTGGAGGCCGAGGCGGTGGGCGGATCAGAGGTCAGGAGTTCGAGACCAG CCTGGCCAATATGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCCTGGCGTGGT GGTGCGTACCTATACTCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATCGCCTGAACCCA GGAGGTGGAGGTTGCAGTGAGCCGAGATCTCACCATTGCACTCCAGCCTGGGTGACAGAG CGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAATAGAAAACAGAGTGTTGCTATGTTGG CCGGGCTGGTCTTGAACTCCTGGGCTCAAGCAGTCCTCCTGCCTTGCCCTCCCAAAGTGC TGGAATTACAGGCCTGAGCCCTTGCACCTGGCTGGGATGGCCTTTTGTTCACACTGGTTT TGTTTCATAATAAAGTGTCAGATGGTTTTGCAAGGAAAGAGACTTTGAAAGAACTGAGCT GCTCCCGGCTCCACCCCCGGCCCAGTCCCAAGGCTCTGCCCTGCACCTGCCCCGTGCCGG GTGTGCCGTGCCTGTGGACGCAGCCGCCCTCCCTCCAGCTGGCATGGCCACTGAGACCTC ACACAGGCGCTTCCTTCCCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGG ATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGGTGGGTGG GGTCCCCTCACCCCACAAAGGCAGGGGAAGTGGGGCAGGGGCTGGCTGCCCGAGAGCTGC GACTGCACCTGGGCCCGCCTCACCTGAGCAGCTACTGGAGGTTGGACCCCTCAGCACCTC TAGAAGCCAGAGGTCAGCCTGGCCCTGGGGCTTTGCCACTCCCTTGCAGTAGCAGGCGGC CTGCCCCACAGGGCCGAGGCCCAGCGCGTGGAGTGGTCTGTGCCGGGGCTGGTGTGCAGG TTTGCGTTCCCAGCGTCCCACCCAAGCAGGTGTGTGAGCCGGGAACTCTGTTGGGAGTCG GCCACTGGGATCCCAGGTGAGGCCGGCTCTGTTGGGGAAGTCGATGTGGAGTCGGCGTGG CCGCTGGGATCCCAGGTGGCTGTAGGTGGCTGTGAGTGTCTGTGGTGTGTTGAGTGGGAA GCCGTGGGTGTTGCCCAGACCTCAGCTGGGGCGTTCTCCTGGTGCCCACGTGCCCCCACC TAGAACGAGACCCCCCTCCGTGAAATGCTGGCGCTTTGGGCACTGCCTGCGGTCCTCACT GAACGAGTCCACTGTTGGTACCGTGACTTTGAGAATGCCTCTCAGTGCCGTCTGTATTTT CTTCACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTT CCCGATCACGTCGCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATCGT CACCGTTAGAGTGAGCATGGCCCCACCACGCCTGGCCCCGGGTGGAAGGCTTTTCTGACA GGGCCCCGTGCTGTCCTGGGGCCGGGTGCTTCCTACACTCTCCTGCACTTAGTGGAGCCC TTCACAGACCACACAGAAGCAAGCATTTGCCTCCCGGGTGGCACCGGAGGTCCTTACTGT CCCTCAGCAGCTGCACCCGGGTGCAGGGGTGGGTGGGGGCCTGGAGGTGCCCAGCACCCA CAGAGCCGTGCCCTGCAGGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTG ATGAACTATGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTG CCAGGTACAGCCGCGCCCCAGGGGCCTGTCTGCGTACAAGTGGGGGCAGGGTCCTGGTCA CCCCCGCGGTGACAGTGCTGCAGGGAGGGCCAGCTGCATCCACAGGGAAAGCCCTGAGAA GCCTCTGTTGCTGCCGAGGCGAGTGGGCCACCCTGAGTGCCCTGGGCTGGGGGCAGCCAG GTCCACATGGGAGCTTCCCTCCCTCCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCT GCGTGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAA CCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGAGCCCCCCTCCGAGTGGCCCATCCCA GGGAGACCTGCCGGGGCCCACTCACAGCCGCCCATCTGTCGTTGCAGGTGGGTGACTTCG GGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCTGT GGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGTGAGTCCTGGGCGTCTGAGTGCCT CCCCTGTCCCCCACGCAGCCTCCCACAGCTTCGCGGGCACTGGCCCTCCTGAACACCTCT CCTGACCTCTTAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGTTGCATCTTCGG GGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAAGTCAGAAATCGATCAGATCAACAA GGTGTTCAAGGTGGGTCTGGCCCTGCTGCAGGTGCGCTGTGGGGTTGTGGAGGAGTTGCA GGAATGGGGCTGCGGGGCGCACAGGTGCTGGGTTGAGATGGGGACCAGGGCCACTGAGAG CCCTCCTGGTGGCTTGTCTTCTCTGACGGGACACAGGTGCCAACACTGTGGGCCACTTGG TGTGGCTGTTGAAGCACCTCTGTCTTTCAGGATCTGGGGACCCCTAGTGAGAAAATCTGG CCCGGCTACAGCGAGCTCCCAGCAGTCAAGAAGATGACCTTCAGCGAGCACCCCTACAAC AACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAG TGAGCCCAGTGCAGCCGGGTGGCGGGAGGTCCCGAGCCATAGCGGTGACTTCCCAGTCCC AGGCCTACCTGCTGGCTCACCACGTTCCAGAACTGCTCTGGTGCCTGGCGTCCCATGCCC TGAGCCCCGTCCCAACACAGCCCATCTTTGGGGGACCCAGTGGAGCACACGAGCACCTCC TGGGCCTCTGGCCCTCTCCCCCCAGGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCG CTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCA TGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGA GGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGTGAGGGGCCTGGCGGGTGGGGCGT GCCCACAGGTGGGGCTGGCTTGGGCAGGGTTCTCACGGTAGCCGACTCGTCCCAGGGTGA CGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCCTCTGCCGC GGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGG OMIM ID 176873