| Entrez gene ID | | 9859 |
|
| Official gene symbol | | CEP170 |
|
| Full name | | centrosomal protein 170kDa |
|
| Aliases | | ,FAM68A,KAB,KIAA0470, |
|
| Gene summary | | The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq] |
|
| Location | | Chromosome: 1 Locus: 1q44 |
|
| Gene position | | 243418708 - 243287730 Map Viewer |
|
| Gene orientation | | minus |
|
| Gene size | | 130979 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 613023 |
|
|
|
