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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FIG4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9896
Official gene symbolFIG4
Full nameFIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
Aliases,ALS11,CMT4J,KIAA0274,SAC3,dJ249I4.1,hSac3,
Gene summaryThe protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q21
Gene position110012424 - 110146634  Map Viewer
Gene orientationplus
Gene size134211 bp
Gene sequence
OMIM ID609390