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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDC6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID990
Official gene symbolCDC6
Full namecell division cycle 6 homolog (S. cerevisiae)
Aliases,CDC18L,HsCDC18,HsCDC6,
Gene summaryThe protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.3
Gene position38444146 - 38459413  Map Viewer
Gene orientationplus
Gene size15268 bp
Gene sequence
OMIM ID602627