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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MFN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9927
Official gene symbolMFN2
Full namemitofusin 2
Aliases,CMT2A,CMT2A2,CPRP1,HSG,KIAA0214,MARF,
Gene summaryThis gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.22
Gene position12040238 - 12073572  Map Viewer
Gene orientationplus
Gene size33335 bp
Gene sequence
OMIM ID608507