Entrez gene ID | | 9953 |
Official gene symbol | | HS3ST3B1 |
Full name | | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 |
Aliases | | ,30ST3B1,3OST3B1, |
Gene summary | | Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p12-p11.2 |
Gene position | | 14204506 - 14249492 Map Viewer |
Gene orientation | | plus |
Gene size | | 44987 bp |
Gene sequence |
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OMIM ID | | 604058 |
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