Entrez gene ID | | 9997 |
Official gene symbol | | SCO2 |
Full name | | SCO cytochrome oxidase deficient homolog 2 (yeast) |
Aliases | | ,MGC125823,MGC125825,SCO1L, |
Gene summary | | Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13.33 |
Gene position | | 50964868 - 50961997 Map Viewer |
Gene orientation | | minus |
Gene size | | 2872 bp |
Gene sequence |
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OMIM ID | | 604272 |