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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CDKN2B (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000079regulation of cyclin-dependent protein kinase activityIDA
GO:0000080G1 phase of mitotic cell cycleTAS
GO:0000086G2/M transition of mitotic cell cycleIMP
GO:0000278mitotic cell cycleTAS
GO:0007050cell cycle arrestIMP
GO:0008285negative regulation of cell proliferationIMP
GO:0014070response to organic cyclic compoundIEA
GO:0030219megakaryocyte differentiationIEP
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathwayIMP
GO:0030858positive regulation of epithelial cell differentiationIEA
GO:0031575mitotic cell cycle G1/S transition checkpointIMP
GO:0031668cellular response to extracellular stimulusIMP
GO:0031670cellular response to nutrientIMP
GO:0034097response to cytokine stimulusIEA
GO:0042326negative regulation of phosphorylationIDA
GO:0050680negative regulation of epithelial cell proliferationIMP
cellular_component
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
molecular_function
GO:0004861cyclin-dependent protein kinase inhibitor activityIDA
GO:0004861cyclin-dependent protein kinase inhibitor activityNAS
GO:0005515protein bindingIPI
GO:0016301kinase activityIEA
GO:0019901protein kinase bindingIPI

Protein-protein interaction details for CDKN2B (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
MAGEA11Two-hybridphysical16189514
CDK4Two-hybridphysical16189514
ARPC3Two-hybridphysical16169070
IKBKAPTwo-hybridphysical16169070
CCDC90BTwo-hybridphysical16169070
KIAA1377Two-hybridphysical16169070
CDK4Two-hybridphysical16169070
CDK4Two-hybridphysical21900206