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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PAICS (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006144 purine base metabolic process TAS GO:0006164 purine nucleotide biosynthetic process IEA GO:0006189 'de novo' IMP biosynthetic process IEA GO:0009113 purine base biosynthetic process TAS GO:0009168 purine ribonucleoside monophosphate biosynthetic process TAS GO:0055086 nucleobase-containing small molecule metabolic process TAS cellular_component GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004638 phosphoribosylaminoimidazole carboxylase activity IEA GO:0004638 phosphoribosylaminoimidazole carboxylase activity TAS GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IEA GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016829 lyase activity IEA GO:0016874 ligase activity IEA

Protein-protein interaction details for PAICS (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CEP76 Two-hybrid physical 16189514 FXR2 Two-hybrid physical 16189514 PAICS Two-hybrid physical 16189514 NUDT18 Two-hybrid physical 16189514 LNX1 Two-hybrid physical 16189514 PSMC4 Affinity Capture-MS physical 17353931 DGKE Affinity Capture-MS physical 17353931 HLA-B Affinity Capture-MS physical 17353931 GNAS Affinity Capture-MS physical 17353931 EPB41 Affinity Capture-MS physical 17353931 TRAF6 Affinity Capture-MS physical 17353931 MCC Affinity Capture-MS physical 17353931 EIF6 Affinity Capture-MS physical 17353931 CHD3 Two-hybrid physical 16169070 MOBKL3 Two-hybrid physical 16169070 PAICS Two-hybrid physical 16169070 UBC Affinity Capture-MS physical 22118674 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572