Home

Search

Browse

RAGs

User guide

FAQs

Links

Questions

Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADRB2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure IEA GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin IDA GO:0002086 diaphragm contraction IEA GO:0003059 positive regulation of the force of heart contraction by epinephrine IEA GO:0006898 receptor-mediated endocytosis IDA GO:0007166 cell surface receptor linked signaling pathway TAS GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity TAS GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger TAS GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway IEA GO:0007190 activation of adenylate cyclase activity IDA GO:0008284 positive regulation of cell proliferation IEA GO:0008333 endosome to lysosome transport TAS GO:0010765 positive regulation of sodium ion transport IEA GO:0030279 negative regulation of ossification IEA GO:0030501 positive regulation of bone mineralization IEA GO:0035249 synaptic transmission, glutamatergic IEA GO:0035811 negative regulation of urine volume IEA GO:0042060 wound healing IEA GO:0043065 positive regulation of apoptosis IEA GO:0043268 positive regulation of potassium ion transport IEA GO:0043410 positive regulation of MAPKKK cascade IDA GO:0045453 bone resorption IEA GO:0045823 positive regulation of heart contraction IEA GO:0045909 positive regulation of vasodilation IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0048633 positive regulation of skeletal muscle tissue growth IEA GO:0050728 negative regulation of inflammatory response IEA GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity IEA GO:0051929 positive regulation of calcium ion transport via voltage-gated calcium channel activity IEA GO:0051930 regulation of sensory perception of pain IEA GO:0060079 regulation of excitatory postsynaptic membrane potential IEA cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005764 lysosome TAS GO:0005768 endosome IEA GO:0005792 microsome IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IDA GO:0005901 caveola IEA GO:0016324 apical plasma membrane IEA GO:0030424 axon IEA GO:0032809 neuronal cell body membrane IEA GO:0042383 sarcolemma IEA GO:0043197 dendritic spine IEA GO:0043235 receptor complex IDA molecular_function GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004930 G-protein coupled receptor activity IEA GO:0004935 adrenergic receptor activity IEA GO:0004941 beta2-adrenergic receptor activity IDA GO:0005515 protein binding IPI GO:0008144 drug binding IEA GO:0008179 adenylate cyclase binding IEA GO:0015459 potassium channel regulator activity IDA GO:0035240 dopamine binding IEA GO:0035255 ionotropic glutamate receptor binding IEA GO:0042803 protein homodimerization activity IDA GO:0051379 epinephrine binding IEA GO:0051380 norepinephrine binding IDA

Protein-protein interaction details for ADRB2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SRC Affinity Capture-Western physical 11013230 OPRD1 Affinity Capture-Western physical 11278447 ADRB2 FRET physical 11278447 OPRD1 FRET physical 11278447 SLC9A3R1 Co-crystal Structure physical 11882663 KCNJ3 Affinity Capture-Western physical 12297500 KCNJ5 Affinity Capture-Western physical 12297500 EIF2B1 Reconstituted Complex physical 9235896 GRB2 Affinity Capture-Western physical 9830057 GRB2 Reconstituted Complex physical 9830057 AKAP12 Reconstituted Complex physical 11309381 AKAP12 Affinity Capture-Western physical 11309381 ADRBK1 Affinity Capture-Western physical 11309381 SLC9A3R1 Reconstituted Complex physical 9671706 SLC9A3R2 Reconstituted Complex physical 9671706 PPP3CA Co-fractionation physical 9880537 AKAP12 Co-fractionation physical 9880537 SLC9A3R1 Reconstituted Complex physical 9560162 GRK6 Biochemical Activity physical 9819198 UBC Affinity Capture-Western physical 18544533 UBC Affinity Capture-Western physical 15331590 UBC Affinity Capture-Western physical 11588219 MDM2 Biochemical Activity physical 11588219 UBC Affinity Capture-Western physical 20559325 ARRDC3 Affinity Capture-Western physical 20559325 NEDD4 Affinity Capture-Western physical 20559325 VHL Affinity Capture-Western physical 19584355 CUL2 Affinity Capture-Western physical 19584355 TCEB1 Affinity Capture-Western physical 19584355 EGLN3 Affinity Capture-Western physical 19584355 EGLN3 Reconstituted Complex physical 19584355 EGLN3 Reconstituted Complex physical 19584355 CAV3 Affinity Capture-Western physical 21362625 UBC Affinity Capture-Western physical 21330366 UBC Co-purification physical 21330366