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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SCAP (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001666response to hypoxiaIEA
GO:0006994positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathwayIMP
GO:0007568agingIEA
GO:0008202steroid metabolic processIEA
GO:0008203cholesterol metabolic processIEA
GO:0032868response to insulin stimulusIEA
GO:0042304regulation of fatty acid biosynthetic processIEA
GO:0045540regulation of cholesterol biosynthetic processIEA
GO:0045541negative regulation of cholesterol biosynthetic processNAS
GO:0045716positive regulation of low-density lipoprotein particle receptor biosynthetic processNAS
cellular_component
GO:0000139Golgi membraneIEA
GO:0005783endoplasmic reticulumNAS
GO:0005789endoplasmic reticulum membraneIEA
GO:0005792microsomeIEA
GO:0005794Golgi apparatusNAS
GO:0012507ER to Golgi transport vesicle membraneIEA
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0016021integral to membraneNAS
GO:0031410cytoplasmic vesicleIEA
GO:0043234protein complexIEA
molecular_function
GO:0005515protein bindingIPI
GO:0051082unfolded protein bindingNAS

Protein-protein interaction details for SCAP (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
INSIG1Affinity Capture-Westernphysical12842885
INSIG1Affinity Capture-Westernphysical18835813
INSIG2Affinity Capture-Westernphysical16549805
INSIG1Affinity Capture-Westernphysical17043353
RNF139Affinity Capture-Westernphysical19706601
SEC24BReconstituted Complexphysical19706601