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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RAPGEF1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity TAS GO:0001568 blood vessel development IEA GO:0007165 signal transduction NAS GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS GO:0016337 cell-cell adhesion IEA GO:0048008 platelet-derived growth factor receptor signaling pathway IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051056 regulation of small GTPase mediated signal transduction IEA cellular_component GO:0005622 intracellular IEA GO:0005768 endosome TAS GO:0005829 cytosol TAS molecular_function GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005515 protein binding IPI GO:0017124 SH3 domain binding IEA

Protein-protein interaction details for RAPGEF1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCAR1 Two-hybrid physical 9748234 HCK Two-hybrid physical 14551197 HCK Reconstituted Complex physical 14551197 HCK Affinity Capture-Western physical 14551197 CRKL Affinity Capture-Western physical 9820532 CRKL Affinity Capture-Western physical 11167825 CRKL Affinity Capture-Western physical 9374471 NEDD9 Affinity Capture-Western physical 9498705 CRKL Affinity Capture-Western physical 8621483 GRB2 Affinity Capture-Western physical 8621483 CRKL Reconstituted Complex physical 8621483 CRK Affinity Capture-Western physical 7512734 CRK Affinity Capture-Western physical 7512734 CRK Far Western physical 7512734 GRB2 Far Western physical 7512734 BCAR1 Reconstituted Complex physical 9748234 BCAR1 Affinity Capture-Western physical 9748234 CRKL Affinity Capture-Western physical 9344843 SHC1 Affinity Capture-Western physical 9344843 CRKL Affinity Capture-Western physical 11466412 CRKL Affinity Capture-Western physical 11466412 CRKL Affinity Capture-Western physical 10753869 GRB2 Two-hybrid physical 20936779