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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HFE (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002474antigen processing and presentation of peptide antigen via MHC class IIEA
GO:0006461protein complex assemblyTAS
GO:0006811ion transportIEA
GO:0006826iron ion transportTAS
GO:0006879cellular iron ion homeostasisTAS
GO:0006898receptor-mediated endocytosisTAS
GO:0006955immune responseIEA
GO:0007565female pregnancyIEA
GO:0010106cellular response to iron ion starvationIEA
GO:0019882antigen processing and presentationIEA
GO:0042446hormone biosynthetic processIEA
GO:0060586multicellular organismal iron ion homeostasisIEA
cellular_component
GO:0005737cytoplasmTAS
GO:0005769early endosomeIDA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0031410cytoplasmic vesicleIDA
GO:0042612MHC class I protein complexIEA
GO:0045177apical part of cellIDA
GO:0045178basal part of cellIDA
GO:0048471perinuclear region of cytoplasmIDA
GO:0055037recycling endosomeIDA
molecular_function
GO:0005515protein bindingIPI

Protein-protein interaction details for HFE (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
TFRCAffinity Capture-Westernphysical9465039
TFRCAffinity Capture-Westernphysical9465039
TFRCReconstituted Complexphysical11027676
TFR2Co-crystal Structurephysical10638746
UBCAffinity Capture-Westernphysical21245296
SYVN1Affinity Capture-Westernphysical21245296