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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HMGB2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001938 positive regulation of endothelial cell proliferation IDA GO:0006265 DNA topological change ISS GO:0006288 base-excision repair, DNA ligation IDA GO:0006309 DNA fragmentation involved in apoptotic nuclear change TAS GO:0006325 chromatin organization NAS GO:0006334 nucleosome assembly NAS GO:0006351 transcription, DNA-dependent IDA GO:0006357 regulation of transcription from RNA polymerase II promoter IDA GO:0006915 apoptosis TAS GO:0006921 cellular component disassembly involved in apoptosis TAS GO:0007283 spermatogenesis IEA GO:0007289 spermatid nucleus differentiation IEA GO:0008584 male gonad development IEA GO:0032075 positive regulation of nuclease activity IDA GO:0033151 V(D)J recombination ISS GO:0043388 positive regulation of DNA binding IDA GO:0043388 positive regulation of DNA binding IEA GO:0045648 positive regulation of erythrocyte differentiation IMP GO:0045654 positive regulation of megakaryocyte differentiation IMP GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0048015 phosphatidylinositol-mediated signaling NAS GO:0048545 response to steroid hormone stimulus IEA GO:0050918 positive chemotaxis IDA GO:0051103 DNA ligation involved in DNA repair ISS GO:0060326 cell chemotaxis IDA GO:0071222 cellular response to lipopolysaccharide IEP cellular_component GO:0000793 condensed chromosome IDA GO:0005615 extracellular space IDA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0043234 protein complex IDA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0003677 DNA binding IMP GO:0003684 damaged DNA binding IDA GO:0003690 double-stranded DNA binding ISS GO:0003697 single-stranded DNA binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0005515 protein binding IPI GO:0008301 DNA bending activity IDA GO:0019904 protein domain specific binding IEA GO:0042056 chemoattractant activity IDA GO:0044212 transcription regulatory region DNA binding IDA GO:0050786 RAGE receptor binding IGI

Protein-protein interaction details for HMGB2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CSNK1A1 Co-purification physical 12062430 POU2F2 Far Western physical 7720710 POU2F2 Reconstituted Complex physical 7720710 POU5F1 Affinity Capture-Western physical 11099378 RAG1 Reconstituted Complex physical 10490593 RAG1 Reconstituted Complex physical 10490593 PGR Reconstituted Complex physical 9671457 NR3C1 Reconstituted Complex physical 9671457 AR Reconstituted Complex physical 9671457 SET Reconstituted Complex physical 11909973 GZMA Reconstituted Complex physical 11909973 CREBBP Biochemical Activity physical 15005629 CHAF1A Affinity Capture-MS physical 21209461 CHAF1A Affinity Capture-Western physical 21209461 CHAF1A Reconstituted Complex physical 21209461 HMGB1 Affinity Capture-Western physical 12517784