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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IDO1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002534cytokine production involved in inflammatory responseIEA
GO:0002666positive regulation of T cell tolerance inductionIEA
GO:0002678positive regulation of chronic inflammatory responseIEA
GO:0002830positive regulation of type 2 immune responseIEA
GO:0006569tryptophan catabolic processTAS
GO:0006954inflammatory responseIEA
GO:0007565female pregnancyTAS
GO:0007610behaviorIEA
GO:0019441tryptophan catabolic process to kynurenineIEA
GO:0032496response to lipopolysaccharideIEA
GO:0032693negative regulation of interleukin-10 productionIEA
GO:0032735positive regulation of interleukin-12 productionIEA
GO:0033555multicellular organismal response to stressIEA
GO:0034276kynurenic acid biosynthetic processIEA
GO:0034641cellular nitrogen compound metabolic processTAS
GO:0043065positive regulation of apoptosisIEA
GO:0046007negative regulation of activated T cell proliferationIEA
GO:0070233negative regulation of T cell apoptosisIEA
cellular_component
GO:0005625soluble fractionIEA
GO:0005737cytoplasmIEA
GO:0005829cytosolIEA
GO:0005829cytosolTAS
GO:0030485smooth muscle contractile fiberIEA
GO:0032421stereocilium bundleIEA
molecular_function
GO:0004833tryptophan 2,3-dioxygenase activityEXP
GO:0004833tryptophan 2,3-dioxygenase activityIEA
GO:0009055electron carrier activityTAS
GO:0016491oxidoreductase activityIEA
GO:0016597amino acid bindingIEA
GO:0019825oxygen bindingIEA
GO:0020037heme bindingIEA
GO:0033754indoleamine 2,3-dioxygenase activityIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for IDO1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PPP1R16ATwo-hybridphysical16169070
UBCAffinity Capture-Westernphysical20691806