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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for KRAS (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000165 MAPKKK cascade TAS GO:0000186 activation of MAPKK activity TAS GO:0007165 signal transduction IEA GO:0007173 epidermal growth factor receptor signaling pathway TAS GO:0007264 small GTPase mediated signal transduction TAS GO:0007265 Ras protein signal transduction TAS GO:0007411 axon guidance TAS GO:0007596 blood coagulation TAS GO:0008286 insulin receptor signaling pathway TAS GO:0019221 cytokine-mediated signaling pathway IEA GO:0035176 social behavior IEA GO:0043406 positive regulation of MAP kinase activity IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0050900 leukocyte migration TAS GO:0051000 positive regulation of nitric-oxide synthase activity IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity IEA GO:0051384 response to glucocorticoid stimulus IEA GO:0051385 response to mineralocorticoid stimulus IEA cellular_component GO:0005739 mitochondrion IEA GO:0005886 plasma membrane TAS GO:0045121 membrane raft IEA molecular_function GO:0000166 nucleotide binding IEA GO:0003924 GTPase activity IEA GO:0005515 protein binding IPI GO:0005525 GTP binding IEA GO:0008321 Ral guanyl-nucleotide exchange factor activity TAS GO:0019002 GMP binding IEA GO:0019003 GDP binding IEA GO:0030275 LRR domain binding IEA

Protein-protein interaction details for KRAS (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RAP1GDS1 Two-hybrid physical 11948427 HNRNPC Two-hybrid physical 16189514 RASSF2 Affinity Capture-Western physical 12732644 RASSF2 Reconstituted Complex physical 12732644 SHOC2 Two-hybrid physical 10783161 PIK3CA Two-hybrid physical 10783161 RALGDS Two-hybrid physical 10783161 RAF1 Two-hybrid physical 10783161 RAF1 Affinity Capture-Western physical 10882715 RASSF5 Reconstituted Complex physical 11857081 RALGDS Two-hybrid physical 7809086 RALGDS Reconstituted Complex physical 7809086 EPB42 Reconstituted Complex physical 3276554 PIK3CG Reconstituted Complex physical 10542052 PIK3CG Affinity Capture-Western physical 10542052 RASGRF2 Reconstituted Complex physical 11238945 DNAJA3 Two-hybrid physical 18624398 PDE4DIP Two-hybrid physical 21900206 CCT7 Two-hybrid physical 21900206 EEF1A1 Two-hybrid physical 21900206 IGSF21 Two-hybrid physical 21900206 CALM1 Affinity Capture-Western physical 11585916 CALM1 Reconstituted Complex physical 11585916 CALM1 Reconstituted Complex physical 12727204 CALM1 Two-hybrid physical 12727204