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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CIITA (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIMP
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0006955immune responseTAS
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0032966negative regulation of collagen biosynthetic processIC
GO:0034341response to interferon-gammaIDA
GO:0045345positive regulation of MHC class I biosynthetic processIDA
GO:0045348positive regulation of MHC class II biosynthetic processIC
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0046677response to antibioticIDA
GO:0060333interferon-gamma-mediated signaling pathwayTAS
cellular_component
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0003677DNA bindingTAS
GO:0003713transcription coactivator activityTAS
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0008022protein C-terminus bindingIPI
GO:0032403protein complex bindingIDA
GO:0033613activating transcription factor bindingIPI
GO:0044212transcription regulatory region DNA bindingIDA

Protein-protein interaction details for CIITA (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NCOA1Affinity Capture-Westernphysical12933903
NCOA1Reconstituted Complexphysical12933903
RFXANKReconstituted Complexphysical11463838
RFXANKAffinity Capture-Westernphysical11463838
RFX5Affinity Capture-Westernphysical11003667
RFXANKAffinity Capture-Westernphysical11003667
XPO1Reconstituted Complexphysical12517958
RFX5Two-hybridphysical9177217
RFX5Far Westernphysical9177217
MAPK1Biochemical Activityphysical18245089
CDK1Biochemical Activityphysical18245089
MAPK3Affinity Capture-Westernphysical18245089
MAPK1Affinity Capture-Westernphysical18245089
MAPK1Affinity Capture-Westernphysical18245089
XPO1Affinity Capture-Westernphysical18245089
HDAC2Affinity Capture-Westernphysical19041327
HDAC2Biochemical Activityphysical19041327
HDAC1Reconstituted Complexphysical12697811
HDAC2Reconstituted Complexphysical12697811
RFX5Reconstituted Complexphysical12697811
SMARCA4Reconstituted Complexphysical12077331
SMARCA4Reconstituted Complexphysical12077331
HDAC4Affinity Capture-Westernphysical15964851
HDAC5Affinity Capture-Westernphysical15964851
HDAC4Affinity Capture-Westernphysical15964851
HDAC2Affinity Capture-Westernphysical17991736
SIN3BAffinity Capture-Westernphysical17991736
GSK3BBiochemical Activityphysical17991736
PSMC5Reconstituted Complexphysical20351748
PSMC5Affinity Capture-Westernphysical20351748
PSMC2Affinity Capture-Westernphysical20351748
PSMC3Affinity Capture-Westernphysical20351748