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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FURIN (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006465signal peptide processingIDA
GO:0006508proteolysisTAS
GO:0007179transforming growth factor beta receptor signaling pathwayTAS
GO:0007219Notch signaling pathwayTAS
GO:0007568agingIEA
GO:0008283cell proliferationIMP
GO:0016485protein processingIDA
GO:0016485protein processingIMP
GO:0016486peptide hormone processingIDA
GO:0017187peptidyl-glutamic acid carboxylationTAS
GO:0019067viral assembly, maturation, egress, and releaseIEP
GO:0030335positive regulation of cell migrationIEA
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathwayIEA
GO:0032455nerve growth factor processingTAS
GO:0032804negative regulation of low-density lipoprotein particle receptor catabolic processIDA
GO:0032902nerve growth factor productionIDA
GO:0032904negative regulation of nerve growth factor productionIDA
GO:0032911negative regulation of transforming growth factor beta1 productionIMP
GO:0032940secretion by cellIDA
GO:0042176regulation of protein catabolic processIMP
GO:0043043peptide biosynthetic processIDA
GO:0043687post-translational protein modificationTAS
GO:0044267cellular protein metabolic processTAS
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0051044positive regulation of membrane protein ectodomain proteolysisIC
GO:0052548regulation of endopeptidase activityIDA
cellular_component
GO:0000139Golgi membraneTAS
GO:0005615extracellular spaceIDA
GO:0005789endoplasmic reticulum membraneIEA
GO:0005794Golgi apparatusIEA
GO:0005796Golgi lumenTAS
GO:0005802trans-Golgi networkIDA
GO:0005886plasma membraneIEA
GO:0009986cell surfaceIDA
GO:0016021integral to membraneIEA
GO:0030140trans-Golgi network transport vesicleIDA
GO:0031985Golgi cisternaIEA
GO:0045121membrane raftIDA
molecular_function
GO:0002020protease bindingIPI
GO:0004175endopeptidase activityIDA
GO:0004252serine-type endopeptidase activityIDA
GO:0004252serine-type endopeptidase activityTAS
GO:0004867serine-type endopeptidase inhibitor activityIDA
GO:0008233peptidase activityIDA
GO:0042277peptide bindingIDA
GO:0046872metal ion bindingIEA
GO:0048406nerve growth factor bindingIDA

Protein-protein interaction details for FURIN (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SERPINB8Reconstituted Complexphysical9442015
AP2M1Reconstituted Complexphysical10593987
PACS1Reconstituted Complexphysical9695949
PACS1Two-hybridphysical9695949