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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RET (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000165 MAPKKK cascade IEA GO:0001657 ureteric bud development IEA GO:0001755 neural crest cell migration IEA GO:0001838 embryonic epithelial tube formation IEA GO:0006468 protein phosphorylation TAS GO:0007156 homophilic cell adhesion IEA GO:0007165 signal transduction TAS GO:0007399 nervous system development IEA GO:0007497 posterior midgut development TAS GO:0010976 positive regulation of neuron projection development IMP GO:0042551 neuron maturation IEA GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0048484 enteric nervous system development IEA GO:0071300 cellular response to retinoic acid IMP GO:0072300 positive regulation of metanephric glomerulus development ISS cellular_component GO:0016020 membrane IEA GO:0016021 integral to membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004713 protein tyrosine kinase activity TAS GO:0004714 transmembrane receptor protein tyrosine kinase activity IEA GO:0004872 receptor activity TAS GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA

Protein-protein interaction details for RET (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID STAT3 Affinity Capture-Western physical 15485908 DOK6 Affinity Capture-Western physical 15286081 DOK5 Affinity Capture-Western physical 15286081 STAT3 Affinity Capture-Western physical 12637586 SRC Affinity Capture-Western physical 10070972 SHC1 Affinity Capture-Western physical 9047384 SHC1 Reconstituted Complex physical 9047384 PTPRF Reconstituted Complex physical 11121408 DOK2 Affinity Capture-Western physical 11470823 DOK4 Affinity Capture-Western physical 11470823 DOK5 Affinity Capture-Western physical 11470823 DOK5 Reconstituted Complex physical 11470823 DOK1 Two-hybrid physical 12087092 DOK1 Reconstituted Complex physical 12087092 DOK1 Affinity Capture-Western physical 12087092 SHC1 Affinity Capture-Western physical 8183561 GRB2 Reconstituted Complex physical 8183561 CRK Reconstituted Complex physical 9393871 PLCG1 Reconstituted Complex physical 8628282 PDLIM7 Affinity Capture-Western physical 12176011 GRB7 Reconstituted Complex physical 8631863 GRB7 Far Western physical 8631863 FRS2 Reconstituted Complex physical 11360177 NRTN Affinity Capture-Western physical 9192898 GFRA1 Reconstituted Complex physical 9192898 GFRA1 Reconstituted Complex physical 10829012 GRB10 Two-hybrid physical 7665556 GRB2 Reconstituted Complex physical 7665556 GRB10 Reconstituted Complex physical 7665556 GRB10 Affinity Capture-Western physical 7665556 STAT3 Affinity Capture-Western physical 11536047 IKBKG Reconstituted Complex physical 20098747 MCRS1 Affinity Capture-Western physical 16186106