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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for STAT5A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000255 allantoin metabolic process ISS GO:0001553 luteinization IEA GO:0006101 citrate metabolic process ISS GO:0006103 2-oxoglutarate metabolic process ISS GO:0006105 succinate metabolic process ISS GO:0006107 oxaloacetate metabolic process ISS GO:0006351 transcription, DNA-dependent TAS GO:0006357 regulation of transcription from RNA polymerase II promoter TAS GO:0006549 isoleucine metabolic process ISS GO:0006573 valine metabolic process ISS GO:0006600 creatine metabolic process ISS GO:0006631 fatty acid metabolic process ISS GO:0007259 JAK-STAT cascade IEA GO:0007565 female pregnancy IEA GO:0007595 lactation IEA GO:0008284 positive regulation of cell proliferation IEA GO:0018108 peptidyl-tyrosine phosphorylation IEA GO:0019218 regulation of steroid metabolic process IEA GO:0019221 cytokine-mediated signaling pathway IEA GO:0019530 taurine metabolic process ISS GO:0019915 lipid storage IEA GO:0030155 regulation of cell adhesion IEA GO:0030856 regulation of epithelial cell differentiation IEA GO:0031667 response to nutrient levels IEA GO:0032825 positive regulation of natural killer cell differentiation IEA GO:0033026 negative regulation of mast cell apoptosis IEA GO:0033077 T cell differentiation in thymus IEA GO:0040014 regulation of multicellular organism growth ISS GO:0040018 positive regulation of multicellular organism growth IEA GO:0042104 positive regulation of activated T cell proliferation IEA GO:0043029 T cell homeostasis IEA GO:0043066 negative regulation of apoptosis IEA GO:0043434 response to peptide hormone stimulus IEA GO:0045086 positive regulation of interleukin-2 biosynthetic process IEA GO:0045471 response to ethanol IEA GO:0045579 positive regulation of B cell differentiation IEA GO:0045588 positive regulation of gamma-delta T cell differentiation IEA GO:0045647 negative regulation of erythrocyte differentiation IEA GO:0045885 positive regulation of survival gene product expression IEA GO:0045931 positive regulation of mitotic cell cycle IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045954 positive regulation of natural killer cell mediated cytotoxicity IEA GO:0046449 creatinine metabolic process ISS GO:0046543 development of secondary female sexual characteristics IEA GO:0046544 development of secondary male sexual characteristics IEA GO:0048541 Peyer's patch development IEA GO:0050729 positive regulation of inflammatory response IEA GO:0060056 mammary gland involution IEA GO:0060376 positive regulation of mast cell differentiation IEA GO:0060740 prostate gland epithelium morphogenesis IEA GO:0060742 epithelial cell differentiation involved in prostate gland development IEA GO:0061180 mammary gland epithelium development IEA GO:0070668 positive regulation of mast cell proliferation IEA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS molecular_function GO:0003690 double-stranded DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0004871 signal transducer activity IEA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0043565 sequence-specific DNA binding IEA

Protein-protein interaction details for STAT5A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID JAK3 Two-hybrid physical 9047382 MAGEA12 Two-hybrid physical 16189514 PRTFDC1 Two-hybrid physical 16189514 ERBB4 Affinity Capture-Western physical 15534001 EGFR Affinity Capture-MS physical 16729043 ERBB4 Affinity Capture-MS physical 16729043 EGFR Affinity Capture-Western physical 16729043 IL2RB Reconstituted Complex physical 10602027 JAK2 Affinity Capture-Western physical 9575217 ESR1 Reconstituted Complex physical 11682624 ESR2 Reconstituted Complex physical 11682624 PTPN11 Reconstituted Complex physical 10617656 PTPN11 Biochemical Activity physical 10617656 CRKL Affinity Capture-Western physical 9837784 CRKL Reconstituted Complex physical 9837784 EGFR Affinity Capture-Western physical 10358079 JAK1 Two-hybrid physical 9047382 JAK2 Two-hybrid physical 9047382 JAK1 Affinity Capture-Western physical 9047382 JAK1 Affinity Capture-Western physical 9047382 JAK1 Reconstituted Complex physical 9047382 JAK2 Reconstituted Complex physical 9047382 BRCA1 Affinity Capture-Western physical 12459499 BRCA2 Affinity Capture-Western physical 12459499 MAPK1 Reconstituted Complex physical 10194762 MAPK1 Affinity Capture-Western physical 10194762 PTPN11 Affinity Capture-Western physical 12060651 MAPK1 Affinity Capture-Western physical 10996427 SHC1 Affinity Capture-Western physical 10996427 NMI Reconstituted Complex physical 9989503 NMI Two-hybrid physical 9989503 NMI Affinity Capture-Western physical 9989503 CD247 Affinity Capture-Western physical 9880255 EPOR Affinity Capture-Western physical 8977232 EPOR Reconstituted Complex physical 8977232 PTPN1 Protein-peptide physical 12237455 NCOA1 Affinity Capture-Western physical 12954634 HDAC1 Affinity Capture-Western physical 12574125 CARM1 Reconstituted Complex physical 18413343 PRMT1 Reconstituted Complex physical 18413343 CARM1 Affinity Capture-Western physical 18413343 PRMT1 Affinity Capture-Western physical 18413343 EPOR PCA physical 15644415 JAK3 Affinity Capture-Western physical 18250158 SMARCA4 Affinity Capture-Western physical 17387179 FGFR2 Affinity Capture-Western physical 21464042 PGR Affinity Capture-Western physical 21464042 FGFR2 Affinity Capture-Western physical 21464042 PGR Affinity Capture-Western physical 21464042 GNB2 Two-hybrid physical 21900206 SQSTM1 Affinity Capture-Western physical 21771882