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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNNI3 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001570vasculogenesisISS
GO:0001980regulation of systemic arterial blood pressure by ischemic conditionsISS
GO:0006874cellular calcium ion homeostasisISS
GO:0006940regulation of smooth muscle contractionIEA
GO:0007507heart developmentISS
GO:0030049muscle filament slidingTAS
GO:0032780negative regulation of ATPase activityIDA
GO:0032780negative regulation of ATPase activityIMP
GO:0055010ventricular cardiac muscle tissue morphogenesisIMP
GO:0060047heart contractionIMP
GO:0060048cardiac muscle contractionIMP
cellular_component
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
GO:0005861troponin complexIDA
GO:0030017sarcomereTAS
GO:0043292contractile fiberIEA
molecular_function
GO:0003779actin bindingIDA
GO:0005515protein bindingIPI
GO:0019855calcium channel inhibitor activityIPI
GO:0019901protein kinase bindingIPI
GO:0019904protein domain specific bindingIPI
GO:0030172troponin C bindingIPI
GO:0031014troponin T bindingIPI
GO:0048306calcium-dependent protein bindingIPI

Protein-protein interaction details for TNNI3 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PKD2L1Two-hybridphysical12809519
TNNI3KTwo-hybridphysical12721663
TNNC1Reconstituted Complexphysical15134451
TNNC1Reconstituted Complexphysical15049709
TNNC1Reconstituted Complexphysical12939162
PKD2L1Affinity Capture-Westernphysical12809519
PKD2L1Reconstituted Complexphysical12809519
TNNI3KAffinity Capture-Westernphysical12721663
PKD2Two-hybridphysical12525172
PKD2Affinity Capture-Westernphysical12525172
PKD2Affinity Capture-Westernphysical12525172
PKD2Reconstituted Complexphysical12525172
TNNC1Co-crystal Structurephysical12060657
TNNC1Protein-peptidephysical12122471
LYSTTwo-hybridphysical11984006
TNNT2Reconstituted Complexphysical11904166