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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for UBE2B (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000209 protein polyubiquitination IMP GO:0001666 response to hypoxia IEA GO:0001701 in utero embryonic development IEA GO:0006281 DNA repair IGI GO:0006301 postreplication repair IDA GO:0006301 postreplication repair NAS GO:0006344 maintenance of chromatin silencing IEA GO:0006511 ubiquitin-dependent protein catabolic process IDA GO:0006511 ubiquitin-dependent protein catabolic process NAS GO:0006513 protein monoubiquitination IMP GO:0006974 response to DNA damage stimulus IDA GO:0007283 spermatogenesis TAS GO:0007288 sperm axoneme assembly IEA GO:0009411 response to UV IGI GO:0010845 positive regulation of reciprocal meiotic recombination IEA GO:0016567 protein ubiquitination IDA GO:0031056 regulation of histone modification IEA GO:0032869 cellular response to insulin stimulus IEA GO:0033128 negative regulation of histone phosphorylation IEA GO:0033522 histone H2A ubiquitination IMP GO:0042493 response to drug IDA GO:0043066 negative regulation of apoptosis IEA GO:0043161 proteasomal ubiquitin-dependent protein catabolic process IDA GO:0043951 negative regulation of cAMP-mediated signaling IDA GO:0050821 protein stabilization IMP GO:0051026 chiasma assembly IEA GO:0051865 protein autoubiquitination IDA GO:0060070 canonical Wnt receptor signaling pathway ISS GO:0070076 histone lysine demethylation IEA GO:0070193 synaptonemal complex organization IEA GO:0070534 protein K63-linked ubiquitination IDA GO:0070936 protein K48-linked ubiquitination IDA GO:0070979 protein K11-linked ubiquitination IDA cellular_component GO:0000785 chromatin ISS GO:0000790 nuclear chromatin IEA GO:0001741 XY body IEA GO:0005634 nucleus IDA GO:0005657 replication fork IDA GO:0005737 cytoplasm IDA GO:0005886 plasma membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004842 ubiquitin-protein ligase activity IDA GO:0004842 ubiquitin-protein ligase activity IMP GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016874 ligase activity IEA GO:0016881 acid-amino acid ligase activity IEA GO:0031625 ubiquitin protein ligase binding IPI

Protein-protein interaction details for UBE2B (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID UBR2 Affinity Capture-Western physical 14585983 MED31 Two-hybrid physical 16169070 UNC119 Two-hybrid physical 16169070 CRMP1 Two-hybrid physical 16169070 UBR1 Two-hybrid physical 16169070 RAD18 Two-hybrid physical 10908344 RAD18 Affinity Capture-Western physical 10908344 RAD18 Two-hybrid physical 10884424 RAD18 Reconstituted Complex physical 10884424 CDKN1B Biochemical Activity physical 19123975 POLH Affinity Capture-MS physical 16824193 POLH Affinity Capture-Western physical 16824193 RAD18 Two-hybrid physical 19549727 UBR3 Two-hybrid physical 19549727 RAD18 Co-crystal Structure physical 21422291 RAD18 Affinity Capture-Western physical 21858012 PCNA Biochemical Activity physical 20064529 BIRC2 Two-hybrid physical 21113135 HIST2H2AC Biochemical Activity physical 20080676 HIST2H2AC Reconstituted Complex physical 20080676 UBR2 Reconstituted Complex physical 20080676 UBR2 Reconstituted Complex physical 20080676 UBR3 Affinity Capture-Western physical 21816346 NBN Affinity Capture-Western physical 21884979 UBC Reconstituted Complex physical 21965653 RNF20 Reconstituted Complex physical 21443952 PCNA Biochemical Activity physical 15359278 RAD18 Affinity Capture-Western physical 15359278 RAD18 Co-crystal Structure physical 21549715 RAD18 Reconstituted Complex physical 21549715 RAD18 Reconstituted Complex physical 21549715