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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HMGA2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001837 epithelial to mesenchymal transition IMP GO:0002062 chondrocyte differentiation IDA GO:0003131 mesodermal-endodermal cell signaling IMP GO:0006284 base-excision repair IDA GO:0006325 chromatin organization TAS GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006355 regulation of transcription, DNA-dependent IMP GO:0007049 cell cycle IEA GO:0007067 mitosis IEA GO:0007095 mitotic cell cycle G2/M transition DNA damage checkpoint IDA GO:0007275 multicellular organismal development TAS GO:0009615 response to virus IEP GO:0010564 regulation of cell cycle process IDA GO:0010628 positive regulation of gene expression IDA GO:0030261 chromosome condensation IEA GO:0031052 chromosome breakage IDA GO:0031507 heterochromatin formation IDA GO:0035978 histone H2A-S139 phosphorylation IDA GO:0035986 senescence-associated heterochromatin focus formation IDA GO:0035987 endodermal cell differentiation IMP GO:0035988 chondrocyte proliferation IDA GO:0040008 regulation of growth IEA GO:0042769 DNA damage response, detection of DNA damage IDA GO:0043065 positive regulation of apoptosis IDA GO:0043066 negative regulation of apoptosis IDA GO:0043392 negative regulation of DNA binding IDA GO:0043922 negative regulation by host of viral transcription IDA GO:0045444 fat cell differentiation IMP GO:0045869 negative regulation of retroviral genome replication IDA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0048333 mesodermal cell differentiation IMP GO:0048762 mesenchymal cell differentiation IMP GO:0048863 stem cell differentiation IEP GO:0051301 cell division IEA GO:0071158 positive regulation of cell cycle arrest IDA GO:0090402 oncogene-induced senescence IDA GO:2000036 regulation of stem cell maintenance IMP GO:2000036 regulation of stem cell maintenance TAS GO:2000648 positive regulation of stem cell proliferation IDA GO:2000648 positive regulation of stem cell proliferation IMP GO:2000679 positive regulation of transcription regulatory region DNA binding IDA GO:2000685 positive regulation of cellular response to X-ray IDA GO:2000774 positive regulation of cellular senescence IMP GO:2001022 positive regulation of response to DNA damage stimulus IDA GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining IDA GO:2001038 regulation of cellular response to drug IDA cellular_component GO:0000228 nuclear chromosome ISS GO:0000785 chromatin IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0032993 protein-DNA complex IDA GO:0035985 senescence-associated heterochromatin focus IDA GO:0071141 SMAD protein complex IDA molecular_function GO:0000975 regulatory region DNA binding IDA GO:0000988 protein binding transcription factor activity IDA GO:0001047 core promoter binding IDA GO:0001071 nucleic acid binding transcription factor activity IDA GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription IDA GO:0003677 DNA binding IEA GO:0003677 DNA binding NAS GO:0003680 AT DNA binding IDA GO:0003680 AT DNA binding IMP GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity IDA GO:0004677 DNA-dependent protein kinase activity IDA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008301 DNA bending activity IDA GO:0008301 DNA bending activity IMP GO:0031492 nucleosomal DNA binding IDA GO:0035497 cAMP response element binding IDA GO:0035500 MH2 domain binding IDA GO:0035501 MH1 domain binding IDA GO:0046332 SMAD binding IPI GO:0051575 5'-deoxyribose-5-phosphate lyase activity IDA GO:0070742 C2H2 zinc finger domain binding IMP

Protein-protein interaction details for HMGA2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RELA Reconstituted Complex physical 12693954 NFKB1 Reconstituted Complex physical 12693954 NFKB1 Far Western physical 12693954 PIAS3 Two-hybrid physical 11390395 PIAS3 Affinity Capture-Western physical 11390395 RB1 Affinity Capture-Western physical 16766265 RB1 Reconstituted Complex physical 16766265 RB1 Far Western physical 16766265 PRMT6 Biochemical Activity physical 16293633 PRMT6 Far Western physical 16293633 NPM1 Far Western physical 16293633 SMAD1 Affinity Capture-Western physical 18425117 SMAD5 Affinity Capture-Western physical 18425117 SMAD9 Affinity Capture-Western physical 18425117 PRKCA Biochemical Activity physical 10889043