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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNFSF10 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006915apoptosisTAS
GO:0006917induction of apoptosisTAS
GO:0006919activation of caspase activityTAS
GO:0006955immune responseIEA
GO:0007165signal transductionTAS
GO:0007267cell-cell signalingTAS
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0008633activation of pro-apoptotic gene productsTAS
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEP
cellular_component
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
GO:0005625soluble fractionTAS
GO:0005887integral to plasma membraneTAS
GO:0016020membraneIEA
molecular_function
GO:0005102receptor bindingTAS
GO:0005125cytokine activityIEA
GO:0005164tumor necrosis factor receptor bindingIEA
GO:0005515protein bindingIPI
GO:0046872metal ion bindingIEA

Protein-protein interaction details for TNFSF10 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ACP5Two-hybridphysical16169070
C7orf64Two-hybridphysical16169070
TNFSF10Co-crystal Structurephysical10651627
TNFRSF10DReconstituted Complexphysical9430226
TNFRSF10BReconstituted Complexphysical11094155
TNFRSF10AAffinity Capture-Westernphysical9082980
TNFRSF10BAffinity Capture-MSphysical9311998
TNFRSF10BCo-crystal Structurephysical10549288
TNFRSF10BReconstituted Complexphysical10549288