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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNFRSF10A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006917 induction of apoptosis NAS GO:0006919 activation of caspase activity NAS GO:0007165 signal transduction IEA GO:0007250 activation of NF-kappaB-inducing kinase activity NAS GO:0008625 induction of apoptosis via death domain receptors NAS GO:0071260 cellular response to mechanical stimulus IEP cellular_component GO:0016020 membrane IEA GO:0016021 integral to membrane IC molecular_function GO:0004872 receptor activity NAS GO:0005035 death receptor activity TAS GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008656 caspase activator activity NAS GO:0045569 TRAIL binding NAS

Protein-protein interaction details for TNFRSF10A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCL10 Two-hybrid physical 10400625 CASP8 Affinity Capture-Western physical 9325248 CASP10 Affinity Capture-Western physical 9325248 CFLAR Affinity Capture-Western physical 9325248 DAP3 Affinity Capture-Western physical 11376335 DAP3 Two-hybrid physical 11376335 TRADD Affinity Capture-Western physical 9430227 FADD Affinity Capture-Western physical 9430227 TNFSF10 Affinity Capture-Western physical 9082980 UBC Affinity Capture-Western physical 19932172 CBL Affinity Capture-Western physical 19932172 CFLAR Affinity Capture-Western physical 19343040 CASP8 Affinity Capture-Western physical 19343040 CASP8 Biochemical Activity physical 19343040