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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001666 response to hypoxia IDA GO:0001701 in utero embryonic development IEA GO:0001821 histamine secretion IEA GO:0001829 trophectodermal cell differentiation IEA GO:0001889 liver development IEA GO:0001890 placenta development IEA GO:0002314 germinal center B cell differentiation IEA GO:0002636 positive regulation of germinal center formation IEA GO:0002686 negative regulation of leukocyte migration IEA GO:0002906 negative regulation of mature B cell apoptosis IEA GO:0006144 purine base metabolic process TAS GO:0006154 adenosine catabolic process IDA GO:0006154 adenosine catabolic process ISS GO:0006157 deoxyadenosine catabolic process IEA GO:0007155 cell adhesion IEA GO:0007568 aging IEA GO:0009117 nucleotide metabolic process IEA GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEA GO:0010460 positive regulation of heart rate IEA GO:0030890 positive regulation of B cell proliferation IEA GO:0032261 purine nucleotide salvage IMP GO:0033089 positive regulation of T cell differentiation in thymus IEA GO:0033632 regulation of cell-cell adhesion mediated by integrin IDA GO:0042110 T cell activation IDA GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep IEA GO:0042542 response to hydrogen peroxide IEA GO:0043066 negative regulation of apoptosis IEA GO:0043101 purine-containing compound salvage TAS GO:0043103 hypoxanthine salvage IBA GO:0043278 response to morphine IEA GO:0045187 regulation of circadian sleep/wake cycle, sleep IEA GO:0045987 positive regulation of smooth muscle contraction IEA GO:0046061 dATP catabolic process IEA GO:0046103 inosine biosynthetic process IDA GO:0046103 inosine biosynthetic process ISS GO:0046111 xanthine biosynthetic process IEA GO:0046638 positive regulation of alpha-beta T cell differentiation IEA GO:0048286 lung alveolus development IEA GO:0048541 Peyer's patch development IEA GO:0048566 embryonic digestive tract development IEA GO:0050728 negative regulation of inflammatory response IEA GO:0050850 positive regulation of calcium-mediated signaling IEA GO:0050862 positive regulation of T cell receptor signaling pathway IEA GO:0055086 nucleobase-containing small molecule metabolic process TAS GO:0060169 negative regulation of adenosine receptor signaling pathway IDA GO:0060407 negative regulation of penile erection IEA GO:0070244 negative regulation of thymocyte apoptosis IEA GO:0070256 negative regulation of mucus secretion IEA cellular_component GO:0005615 extracellular space IEA GO:0005737 cytoplasm IDA GO:0005764 lysosome IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0009897 external side of plasma membrane IDA GO:0009986 cell surface IDA GO:0016020 membrane IDA GO:0030054 cell junction IEA GO:0031410 cytoplasmic vesicle IEA GO:0032839 dendrite cytoplasm IEA GO:0043025 neuronal cell body IEA GO:0060205 cytoplasmic membrane-bounded vesicle lumen IEA molecular_function GO:0001883 purine nucleoside binding IEA GO:0004000 adenosine deaminase activity IDA GO:0004000 adenosine deaminase activity IEA GO:0004000 adenosine deaminase activity ISS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IMP GO:0008270 zinc ion binding ISS GO:0016787 hydrolase activity IEA GO:0019239 deaminase activity IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for ADA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ADORA1 Co-localization physical 12150791 DRD1 Co-localization physical 12150791 NR3C1 Reconstituted Complex physical 9154805 ADORA2A Affinity Capture-Western physical 11125033